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DNMT3L 抗体 (C-Term)

TRDMT1 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN356577
发货至: 中国
  • 抗原 See all DNMT3L (TRDMT1) 抗体
    DNMT3L (TRDMT1) (DNA (Cytosine-5-)-Methyltransferase 3 Like (TRDMT1))
    抗原表位
    • 15
    • 9
    • 8
    • 7
    • 7
    • 6
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 388-417, C-Term
    适用
    • 67
    • 17
    • 2
    • 1
    宿主
    • 66
    • 6
    克隆类型
    • 68
    • 4
    多克隆
    标记
    • 34
    • 7
    • 6
    • 6
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DNMT3L antibody is un-conjugated
    应用范围
    • 65
    • 38
    • 16
    • 13
    • 13
    • 7
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody is specific to Dnmt3L (C-term).
    纯化方法
    Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
    免疫原
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 388~417 amino acids from the C-terminal region of Human Dnmt3L. Genename: DNMT3L
    亚型
    Ig Fraction
    Top Product
    Discover our top product TRDMT1 Primary Antibody
  • 应用备注
    ELISA: 1/1,000. Western Bot: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    PBS containing 0.09 % (W/V) Sodium Azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原
    DNMT3L (TRDMT1) (DNA (Cytosine-5-)-Methyltransferase 3 Like (TRDMT1))
    别名
    DNMT3L (TRDMT1 产品)
    别名
    DNMT3L antibody, D6Ertd14e antibody, ecat7 antibody, DNA methyltransferase 3 like antibody, DNA (cytosine-5-)-methyltransferase 3-like antibody, DNMT3L antibody, Dnmt3l antibody
    背景
    CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a nuclear protein with similarity to DNA methyltransferases. This protein is not thought to function as a DNA methyltransferase as it does not contain the amino acid residues necessary for methyltransferase activity. However, this protein does stimulate de novo methylation by DNA cytosine methyltransferase 3 alpha and it is thought to be required for the establishment of maternal genomic imprints. This protein also mediates transcriptional repression through interaction with histone deacetylase 1. Alternative splicing results in two transcript variants. An additional splice variant has been described but its biological validity has not been determined.Synonyms: DNA (cytosine-5)-methyltransferase 3-like
    基因ID
    29947, 9606
    UniProt
    Q9UJW3
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