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EHMT1 抗体 (N-Term)

This 兔 多克隆 anti-EHMT1 antibody specifically detects EHMT1 in WB 和 EIA. The antibody is reactive with 人 samples.
产品编号 ABIN356541
发货至: 中国
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Quick Overview for EHMT1 抗体 (N-Term) (ABIN356541)

抗原

See all EHMT1 抗体
EHMT1 (Euchromatic Histone-Lysine N-Methyltransferase 1 (EHMT1))

适用

  • 66
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  • 1

宿主

  • 42
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克隆类型

  • 44
  • 22
多克隆

标记

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  • 1
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This EHMT1 antibody is un-conjugated

应用范围

  • 65
  • 35
  • 13
  • 5
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  • 1
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Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 7
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    N-Term

    特异性

    This antibody is specific to EHMT1 (N-term).

    纯化方法

    Protein A Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

    免疫原

    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human EHMT1.

    亚型

    Ig Fraction
  • 应用备注

    ELISA: 1/1,000. Western Blot: 1/50-1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS containing 0.09 % (W/V) Sodium Azide as preservative.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原

    EHMT1 (Euchromatic Histone-Lysine N-Methyltransferase 1 (EHMT1))

    别名

    EHMT1

    背景

    EHMT1, also known as EUHMTASE1, is a histone methyltransferase. This protein methylates 'Lys-9' of histone H3 in vitro. H3 'Lys-9' methylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 proteins to methylated histones. EHMT1 is Probably targeted to histone H3 by different DNA-binding proteins like E2F6, MGA, MAX and/or DP1. During G0 phase, it probably contributes to silencing of MYC- and E2F-responsive genes, suggesting a role in the G0/G1 transition of the cell cycle.Synonyms: EUHMTASE1, Eu-HMTase1, Euchromatic histone-lysine N-methyltransferase 1, G9a-like protein 1, GLP, GLP1, H3-K9-HMTase 5, Histone H3-K9 methyltransferase 5, Histone-lysine N-methyltransferase EHMT1, KIAA1876, KMT1D, Lysine N-methyltransferase 1D

    基因ID

    79813, 9606

    UniProt

    Q9H9B1
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