Transferrin 抗体
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北京 101111
Quick Overview for Transferrin 抗体 (ABIN356489)
抗原
See all Transferrin (TF) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody is specific for Transferrin (TF).
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纯化方法
- Protein A Chromatography.
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免疫原
- Purified human transferrin.
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亚型
- IgG
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应用备注
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Suitable for use in Immunoprecipitation and ELISA (1/1,000-1/10,000).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 2.0 mg/mL
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缓冲液
- PBS, pH 7.4 containing 0.05 % Sodium Azide as preservative and 1 % BSA as stabilizer.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- Transferrin (TF)
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背景
- Transferrin is a blood plasma protein for iron ion delivery. It is a is a glycoprotein, which binds iron very tightly but reversibly. Transferrin has a molecular weight of around 80 kilo Daltons and contains 2 specific high affinity Fe (III) binding sites. It is synthesized in the liver and consists of two domains each having a high affinity reversible binding site for Fe3+. The iron is transported in blood and interstitial fluids to sites of use and disposal. Iron/Transferrin is essential in hemoglobin synthesis and for certain types of cell division. Serum concentration rises in iron deficiency and pregnancy and falls in iron overload, infection and inflammatory conditions. When a transferrin protein loaded with iron encounters a transferrin receptor on the surface of a cell (importantly, to erythroid precursors in the bone marrow), it binds to it and is consequently transported into the cell in a vesicle.Synonyms: Beta-1 metal-binding globulin, Serotransferrin, Siderophilin
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基因ID
- 7018
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NCBI登录号
- NP_001054
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UniProt
- P02787
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途径
- Transition Metal Ion Homeostasis
抗原
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