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EPH Receptor A5 抗体

EPHA5 适用: 人 WB, IHC (p), EIA 宿主: 小鼠 Monoclonal 46CT61-6-4 unconjugated
产品编号 ABIN356398
发货至: 中国
  • 抗原 See all EPH Receptor A5 (EPHA5) 抗体
    EPH Receptor A5 (EPHA5)
    适用
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    宿主
    • 70
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    小鼠
    克隆类型
    • 70
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    单克隆
    标记
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    This EPH Receptor A5 antibody is un-conjugated
    应用范围
    • 68
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody is specific to EPHA5.
    产品特性
    Synonyms: Ephrin type-A receptor 5, Tyrosine-protein kinase receptor EHK-1, Eph homology kinase-1,Receptor protein-tyrosine kinase HEK7
    纯化方法
    Protein G Chromatography eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
    免疫原
    Purified His-tagged EPHA5 protein(Fragment).
    克隆位点
    46CT61-6-4
    亚型
    IgG1
    Top Product
    Discover our top product EPHA5 Primary Antibody
  • 应用备注
    ELISA: 1/4,000. Western blotting: 1/2000. Immunohistochemistry.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    PBS containing 0.09 % (W/V) Sodium Azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.
    有效期
    12 months
  • 抗原
    EPH Receptor A5 (EPHA5)
    别名
    EPHA5 (EPHA5 产品)
    别名
    CEK7 antibody, EHK-1 antibody, EHK1 antibody, EK7 antibody, HEK7 antibody, TYRO4 antibody, AI854630 antibody, AW125296 antibody, Cek7 antibody, Ehk1 antibody, Els1 antibody, Hek7 antibody, Rek7 antibody, bsk antibody, Els1. antibody, EPHA5 antibody, EPH receptor A5 antibody, Eph receptor A5 antibody, EPHA5 antibody, epha5 antibody, Epha5 antibody
    背景
    EPHA5 belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, adhesion, motility and death. There are currently about 90 TK genes sequenced, 58 are of receptor protein TK (e.g. EGFR, EPH, FGFR, PDGFR, TRK, and VEGFR families), and 32 of cytosolic TK (e.g. ABL, FAK, JAK, and SRC families).Synonyms: EHK1, EPH homology kinase 1, Ephrin type-A receptor 5, HEK7, Receptor protein-tyrosine kinase HEK7, Tyrosine-protein kinase receptor EHK-1
    基因ID
    2044
    UniProt
    P54756
    途径
    RTK signaling
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