EPH Receptor A5 抗体
Quick Overview for EPH Receptor A5 抗体 (ABIN356398)
抗原
See all EPH Receptor A5 (EPHA5) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody is specific to EPHA5.
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产品特性
- Synonyms: Ephrin type-A receptor 5, Tyrosine-protein kinase receptor EHK-1, Eph homology kinase-1,Receptor protein-tyrosine kinase HEK7
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纯化方法
- Protein G Chromatography eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
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免疫原
- Purified His-tagged EPHA5 protein(Fragment).
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亚型
- IgG1
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anti-EPH Receptor A5 (EPHA5) (AA 246-514) antibody
EPHA5 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor A5 (EPHA5) antibodyEPHA5 适用: 人 WB, IHC (p) 宿主: 小鼠 Monoclonal 6C4 unconjugated
anti-EPH Receptor A5 (EPHA5) (Internal Region) antibodyEPHA5 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor A5 (EPHA5) (AA 1-130) antibodyEPHA5 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor A5 (EPHA5) (AA 620-774) antibodyEPHA5 适用: 人 ELISA 宿主: 小鼠 Monoclonal 8B10B1 unconjugated
anti-EPH Receptor A5 (EPHA5) (AA 942-972), (C-Term) antibodyEPHA5 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB1658 unconjugated
anti-EPH Receptor A5 (EPHA5) (AA 234-333) antibodyEPHA5 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5C8 unconjugated
anti-EPH Receptor A5 (EPHA5) (AA 234-333) antibodyEPHA5 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5C3 unconjugated
anti-EPH Receptor A5 (EPHA5) (AA 792-841) antibodyEPHA5 适用: 人, 小鼠, 大鼠, 小鸡, 猴, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼, Bat, Pig, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor A5 (EPHA5) (AA 1001-1032), (C-Term) antibodyEPHA5 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- ELISA: 1/4,000. Western blotting: 1/2000. Immunohistochemistry.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS containing 0.09 % (W/V) Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
有效期
- 12 months
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- EPH Receptor A5 (EPHA5)
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别名
- EPHA5
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背景
- EPHA5 belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, adhesion, motility and death. There are currently about 90 TK genes sequenced, 58 are of receptor protein TK (e.g. EGFR, EPH, FGFR, PDGFR, TRK, and VEGFR families), and 32 of cytosolic TK (e.g. ABL, FAK, JAK, and SRC families).Synonyms: EHK1, EPH homology kinase 1, Ephrin type-A receptor 5, HEK7, Receptor protein-tyrosine kinase HEK7, Tyrosine-protein kinase receptor EHK-1
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基因ID
- 2044
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UniProt
- P54756
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途径
- RTK signaling
抗原
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