LIN28A 抗体
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北京 101111
Quick Overview for LIN28A 抗体 (ABIN356385)
抗原
See all LIN28A 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody is specific to LIN28A.
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产品特性
- Synonyms: LIN-28, LIN28A, CSDD1, ZCCHC1, Lin-28 homolog A
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纯化方法
- Protein G Chromatography eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
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免疫原
- LIN28A recombinant protein is used to produce this monoclonal antibody.
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亚型
- IgG1
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应用备注
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ELISA: 1/10000. Western blotting: 1/200-1/2000. Immunohistochemistry: 1/50-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS containing 0.09 % (W/V) Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
有效期
- 12 months
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- LIN28A (Lin-28 Homolog A (C. Elegans) (LIN28A))
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别名
- LIN28
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背景
- LIN28A acts as a 'translational enhancer', driving specific mRNAs to polysomes and thus increasing the efficiency of protein synthesis. Its association with the translational machinery and target mRNAs results in an increased number of initiation events per molecule of mRNA and, indirectly, in stabilizing the mRNAs. Binds IGF2 mRNA, MYOD1 mRNA, ARBP/36B4 ribosomal protein mRNA and its own mRNA. It is essential for skeletal muscle differentiation through the translational up-regulation of IGF2 expression.Synonyms: CSDD1, LIN-28, LIN28A, Lin-28 homolog A, ZCCHC1
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基因ID
- 79727
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UniProt
- Q9H9Z2
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途径
- Stem Cell Maintenance
抗原
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