SUV39H1 抗体 (N-Term)
Quick Overview for SUV39H1 抗体 (N-Term) (ABIN356373)
抗原
See all SUV39H1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- N-Term
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特异性
- This antibody is specific to SUV39H1.
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产品特性
- Synonyms: SUV39H, Lysine N-methyltransferase 1A, Histone-lysine N-methyltransferase SUV39H1,Histone H3-K9 methyltransferase 1, Position-effect variegation 3-9 homolog, Suppressor ofvariegation 3-9 homolog 1
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纯化方法
- Protein G Chromatography eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
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免疫原
- This antibody was raised using purified recombinant GST fusion protein encodingN-terminal of human SUV39H1.
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亚型
- IgG1
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anti-Suppressor of Variegation 3-9 Homolog 1 (Drosophila) (SUV39H1) antibody
SUV39H1 适用: 人, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Variegation 3-9 Homolog 1 (Drosophila) (SUV39H1) (AA 179-412) antibodySUV39H1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Variegation 3-9 Homolog 1 (Drosophila) (SUV39H1) (C-Term) antibodySUV39H1 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Variegation 3-9 Homolog 1 (Drosophila) (SUV39H1) (C-Term) antibodySUV39H1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔, 斑马鱼, Hamster, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Variegation 3-9 Homolog 1 (Drosophila) (SUV39H1) (AA 1-220) antibodySUV39H1 适用: 人 WB, IHC, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Variegation 3-9 Homolog 1 (Drosophila) (SUV39H1) (C-Term) antibodySUV39H1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Variegation 3-9 Homolog 1 (Drosophila) (SUV39H1) (AA 108-157) antibodySUV39H1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔, 马, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Variegation 3-9 Homolog 1 (Drosophila) (SUV39H1) (N-Term) antibodySUV39H1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB2153 unconjugated
anti-Suppressor of Variegation 3-9 Homolog 1 (Drosophila) (SUV39H1) (N-Term) antibodySUV39H1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Variegation 3-9 Homolog 1 (Drosophila) (SUV39H1) (N-Term) antibodySUV39H1 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- ELISA: 1/1,000. Western blotting: 1/100-1/500.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS containing 0.09 % (W/V) Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
有效期
- 12 months
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- SUV39H1 (Suppressor of Variegation 3-9 Homolog 1 (Drosophila) (SUV39H1))
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别名
- SUV39H1 / KMT1A
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背景
- Similar to acetylation and phosphorylation, histone methylation at the N-terminal tail has emerged as an important role in regulating chromatin dynamics and gene activity. Histone methylation occurs on arginine and lysine residues and is catalyzed by two families of proteins, the protein arginine methyltransferase family and the SET-domain-containing methyltransferase family. Five members have been identified in the arginine methyltransferase family. About 27 are grouped into the SET-domain family, and another 17 make up the PR domain family that is related to the SET domain family. The retinoblastoma protein-interacting zinc finger geneRIZ1 is a tumor suppressor gene and a FOUNDING member of the PR domain family. RIZ1 inactivation is commonly found in many types of human cancers and occurs through loss of mRNA expression, frame shift mutation, chromosomal deletion, and missense mutation. RIZ1 is also a tumor susceptibility gene in mice. The loss of RIZ1 mRNA in human cancers was shown to associate with DNA methylation of its promoter CpG island. Methylation of the RIZ1 promoter strongly correlated with lost or decreased RIZ1 mRNA expression in breast, liver, colon, and lung cancer cell lines as well as in liver cancer tissues.Synonyms: Histone H3-K9 methyltransferase 1, Histone-lysine N-methyltransferase SUV39H1, Lysine N-methyltransferase 1A, Position-effect variegation 3-9 homolog, SUV39H, Suppressor of variegation 3-9 homolog 1
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基因ID
- 6839
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UniProt
- O43463
抗原
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