HMGB1 抗体 (N-Term)
Our Local Distributor
北京 101111
Quick Overview for HMGB1 抗体 (N-Term) (ABIN356226)
抗原
See all HMGB1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 1-215, N-Term
-
特异性
- The antibody recognizes human HMGB1. Other species not tested.
-
产品特性
- Synonyms: High mobility group protein 1, HMG1, HMG-1, High mobility group protein B1, HMGB-1,Amphoterin
-
纯化方法
- Protein-G affinity chromatography
-
免疫原
- Recombinant human HMGB1 (1-215aa) purified from High Five (Trichoplusia ni) insect cells.
-
亚型
- IgG2b
-
-
-
-
应用备注
-
ELISA. Western blot (1: 500 - 1: 2,000), recommended starting dilution is 1: 1,000. Immunohistochemistry (1: 100 - 1: 300), recommended starting dilution is 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1.0 mg/mL
-
缓冲液
- PBS, pH 7.4, containing 0.09 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C/-20 °C
-
储存方法
-
Store the antibody undiluted at 2-8 °C for up to two weeks or (in aliquots) at -20 °C or -70 °Cfor longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
有效期
- 12 months
-
-
- HMGB1 (High Mobility Group Box 1 (HMGB1))
-
别名
- HMGB1
-
背景
- High mobility group box1 protein (HMGB1) is a very abundant chromatin-binding protein residing in the eukaryotic cell nucleus and acting in the assembly of nucleoprotein complexes. Inside the cell, HMGB1 binds to DNA and has a role in transcriptional regulation. Outside the cell, HMGB1 acts as a cytokine and has activities that resemble those of tumor necrosis factor.Synonyms: Amphoterin, HMG-1, HMG1, HMGB-1, High mobility group protein 1, High mobility group protein B1
-
基因ID
- 3146
-
UniProt
- P09429
-
途径
- p53 Pathway, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Toll-Like Receptors Cascades, Smooth Muscle Cell Migration, Inflammasome
抗原
-