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CUL9 抗体 (C-Term)

This anti-CUL9 antibody is a 兔 多克隆 antibody detecting CUL9 in WB, IHC 和 ELISA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN356104
发货至: 中国

Quick Overview for CUL9 抗体 (C-Term) (ABIN356104)

抗原

See all CUL9 抗体
CUL9 (Cullin 9 (CUL9))

适用

  • 24
  • 7
  • 2
  • 1
人, 小鼠, 大鼠

宿主

  • 18
  • 7

克隆类型

  • 18
  • 7
多克隆

标记

  • 25
This CUL9 antibody is un-conjugated

应用范围

  • 24
  • 13
  • 12
  • 8
  • 7
  • 4
  • 4
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 抗原表位

    • 7
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term

    交叉反应

    人, 小鼠, 大鼠

    纯化方法

    affinity purified

    免疫原

    17 amino acid synthetic peptide from near the carboxy terminus of human PARC.

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    储存条件

    -20 °C
  • 抗原

    CUL9 (Cullin 9 (CUL9))

    别名

    PARC/P53-associated Parkin-like Cytoplasmic Protein

    背景

    PARC (p53 associated parkin like cytoplasmic protein) antibody directly interacted and formed an approximately 1MD complex with p53 in the cytoplasm of unstressed cells. In the absence of stress, inactivation of PARC induced nuclear localization of endogenous p53 and activated p53 dependent apoptosis. Overexpression of PARC promoted cytoplasmic sequestration of ectopic p53. Furthermore, abnormal cytoplasmic localization of p53 was observed in a number of neuroblastoma cell lines, RNA interference-mediated reduction of endogenous PARC significantly sensitized these neuroblastoma cells in the DNA damage response. These results revealed that PARC is a critical regulator in controlling p53 subcellular localization and subsequent function.
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