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NGFR 抗体

NGFR 适用: 人 WB, FACS, IHC, Purif 宿主: 小鼠 Monoclonal unconjugated
产品编号 ABIN350715
发货至: 中国
  • 抗原 See all NGFR 抗体
    NGFR (Nerve Growth Factor Receptor (NGFR))
    适用
    • 155
    • 65
    • 57
    • 28
    • 26
    • 26
    • 25
    • 21
    • 11
    • 5
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    • 3
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    • 1
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    宿主
    • 87
    • 75
    • 4
    • 1
    小鼠
    克隆类型
    • 93
    • 74
    单克隆
    标记
    • 85
    • 14
    • 11
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
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    • 1
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    This NGFR antibody is un-conjugated
    应用范围
    • 91
    • 82
    • 56
    • 46
    • 41
    • 28
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    • 19
    • 16
    • 15
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    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), Purification (Purif)
    特异性
    Specific for p75NTR.
    交叉反应
    Cat, 犬, 人, Marmoset, Pig, 兔
    纯化方法
    Affinity purified
    免疫原
    Human melanoma cell lines
    亚型
    IgG1, IgG1 kappa
    Top Product
    Discover our top product NGFR Primary Antibody
  • 应用备注
    IHC, WB, FC. A concentration of 2-10 μg,ml is recommended. The optimal working concentration should be determined by the end user. This antibody may also be used for immunoabsorptive purification of NGF-receptors. See also the eLab Book at the end of this page.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstitute in 150 µL of sterile water. Centrifuge to remove any insoluble material.
    注意事项
    Avoid freeze and thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
    有效期
    12 months
  • 抗原
    NGFR (Nerve Growth Factor Receptor (NGFR))
    别名
    p75NTR (NGFR 产品)
    背景
    FUNCTION: Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells. SUBUNIT: Homodimer, disulfide-linked. Interacts with p75NTR-associated cell death executor. Interacts with TRAF2, TRAF4, TRAF6, PTPN13 and RANBP9. Interacts through TRAF6 with SQSTM1 which bridges NGFR to NTRK1. Interacts with BEX1 and NGFRAP1/BEX3. SUBCELLULAR LOCATION: Membrane, Single-pass type I membrane protein.,Olfactory Related,Tumor necrosis factor receptor superfamily member 16, P08138, low-affinity nerve growth factor receptor, NGF receptor, Gp80-LNGFR, p75 ICD, low affinity neurotrophin receptor p75NTR, CD271 antigen, NGFR, TNFRSF16
    UniProt
    P08138
    途径
    NF-kappaB Signaling, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Growth Factor Binding
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