LC3C 抗体
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北京 101111
Quick Overview for LC3C 抗体 (ABIN7698496)
抗原
See all LC3C (MAP1LC3C) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Sheep antibody to MAP1LC3C
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特异性
- Specific for MAP1LC3C.
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交叉反应
- 人
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交叉反应 （详细）
- Other species not yet tested.
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纯化方法
- IgG
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免疫原
- A synthetic peptide from human microtubule-associated protein 1 light chain 3 gamma (MAP1LC3C MAP1A/MAP1B LC3 C) conjugated to an immunogenic carrier protein has been used as the immunogen.
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亚型
- IgG
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anti-Microtubule-Associated Protein 1 Light Chain 3 gamma (MAP1LC3C) (pSer12) antibody
MAP1LC3C 适用: 人 WB, DB 宿主: 兔 Polyclonal RB10838-RB16769 unconjugated
anti-Microtubule-Associated Protein 1 Light Chain 3 gamma (MAP1LC3C) (AA 1-30) antibodyMAP1LC3C 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Microtubule-Associated Protein 1 Light Chain 3 gamma (MAP1LC3C) (pSer12) antibodyMAP1LC3C 适用: 人 ELISA, WB, DB 宿主: 兔 Polyclonal unconjugated
anti-Microtubule-Associated Protein 1 Light Chain 3 gamma (MAP1LC3C) (Thr48) antibodyMAP1LC3C 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Microtubule-Associated Protein 1 Light Chain 3 gamma (MAP1LC3C) (AA 1-147) antibodyMAP1LC3C 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Microtubule-Associated Protein 1 Light Chain 3 gamma (MAP1LC3C) (pSer12) antibodyMAP1LC3C 适用: 人 WB, DB 宿主: 兔 Polyclonal unconjugated
anti-Microtubule-Associated Protein 1 Light Chain 3 gamma (MAP1LC3C) (AA 1-147) antibodyMAP1LC3C 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Microtubule-Associated Protein 1 Light Chain 3 gamma (MAP1LC3C) (AA 1-30), (N-Term) antibodyMAP1LC3C 适用: 人, 大鼠, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- IHC WB. Use at a concentration of 10-50,micro,g,ml. The optimal working concentration should be determined by the end user. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material.
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注意事项
- Avoid freeze and thaw cycles.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
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有效期
- 12 months
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- LC3C (MAP1LC3C) (Microtubule-Associated Protein 1 Light Chain 3 gamma (MAP1LC3C))
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别名
- MAP1LC3C
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背景
- Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation metamorphosis non-apoptotic cell death and aging. Reduced levels of autophagy have been described in some malignant tumors and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. FUNCTION: Probably involved in formation of autophagosomal vacuoles (autophagosomes). SUBUNIT: 3 different light chains LC1 LC2 and LC3 can associate with MAP1A and MAP1B proteins. SUBCELLULAR LOCATION: Cytoplasm. Intracytoplasmic membrane, Lipid-anchor. Cytoplasmic vesicle autophagosome membrane, Lipid-anchor. Note: LC3-II binds to the autophagic membranes. TISSUE SPECIFICITY: Most abundant in placenta lung and ovary. The precursor molecule is cleaved by APG4B/ATG4B to form the cytosolic form LC3-I. This is activated by APG7L/ATG7 transferred to ATG3 and conjugated to phospholipid to form the membrane-bound form LC3-II.
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UniProt
- Q9BXW4
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途径
- Autophagy
抗原
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