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Desmin 抗体 (C-Term)

This anti-Desmin antibody is a 兔 多克隆 antibody detecting Desmin in WB 和 IHC. Suitable for 小鼠.
产品编号 ABIN350288
发货至: 中国
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Quick Overview for Desmin 抗体 (C-Term) (ABIN350288)

抗原

See all Desmin (DES) 抗体
Desmin (DES)

适用

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小鼠

宿主

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克隆类型

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多克隆

标记

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This Desmin antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    C-Term

    特异性

    Specific for Desmin.

    交叉反应

    人, 小鼠, 大鼠

    交叉反应 (详细)

    Other species not yet tested.

    纯化方法

    IgG

    免疫原

    A synthetic peptide from c-terminal region of mouse Desmin conjugated to an immunogenic carrier protein was used as the antigen. The antigen is homologous in human and rat.

    亚型

    IgG
  • 应用备注

    IHC, WB. A concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Reconstitute in 1000 μL of sterile water. Centrifuge to remove any insoluble material.

    注意事项

    Avoid freeze and thaw cycles.

    储存条件

    4 °C/-20 °C

    储存方法

    Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

    有效期

    12 months
  • 抗原

    Desmin (DES)

    别名

    Desmin

    背景

    Function: Desmin are class-III intermediate filaments found in muscle cells. In adult striated muscle they form a fibrous network connecting myofibrils to each other and to the plasma membrane from the periphery of the Z-line structures. Defects in DES are the cause of desmin-related cardio-skeletal myopathy (CSM), also known as desmin-related myopathy (DRM). CSM is characterized by skeletal muscle weakness associated with cardiac conduction blocks, arrhythmias, restrictive heart failure, and by intracytoplasmic accumulation of desmin-reactive deposits in cardiac and skeletal muscle cells. A desmin-related myopathy can have a distal onset, it is then known as hereditary distal myopathy (HDM). Defects in DES are the cause of neurogenic scapuloperoneal syndrome Kaeser type (Kaeser syndrome). Subcellular location: Cytoplasm.,Stem Cells,Des

    UniProt

    P31001
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