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Dynactin 1 抗体 (AA 120-170)

The 兔 多克隆 anti-Dynactin 1 antibody (ABIN7698950) specifically detects Dynactin 1 in WB 和 IHC. The antibody is reactive with 人 samples.
产品编号 ABIN7698950
发货至: 中国
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Quick Overview for Dynactin 1 抗体 (AA 120-170) (ABIN7698950)

抗原

See all Dynactin 1 (DCTN1) 抗体
Dynactin 1 (DCTN1)

适用

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宿主

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克隆类型

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多克隆

标记

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This Dynactin 1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    AA 120-170

    原理

    Rabbit antibody to DCTN1 (120-170)

    特异性

    Specific for DCTN1.

    交叉反应

    人, 小鼠, 大鼠

    交叉反应 (详细)

    Other species not yet tested.

    纯化方法

    IgG

    免疫原

    A synthetic peptide from AA 120-170 of human DCTN1 conjugated to an immunogenic carrier protein was used as the antigen. The peptide is homologous in rat and moue.

    亚型

    IgG
  • 应用备注

    IHC WB. A concentration of 10-50,micro,g,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material.

    注意事项

    Avoid freeze and thaw cycles.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

    有效期

    12 months
  • 抗原

    Dynactin 1 (DCTN1)

    别名

    DCTN1

    背景

    FUNCTION: Required for the cytoplasmic dynein-driven retrograde movement of vesicles and organelles along microtubules. Dynein-dynactin interaction is a key component of the mechanism of axonal transport of vesicles and organelles. SUBUNIT: Large macromolecular complex of at least 10 components, p150(glued) binds directly to microtubules and to cytoplasmic dynein. Interacts with the C-terminus of MAPRE1 MAPRE2 and MAPRE3. SUBCELLULAR LOCATION: Cytoplasm. Cytoplasm cytoskeleton. TISSUE SPECIFICITY: Brain. DISEASE: Defects in DCTN1 are the cause of progressive lower motor neuron disease. PLMND is a progressive dominant disease that has no sensory symptoms.

    UniProt

    Q14203

    途径

    M Phase, ER-Nucleus Signaling
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