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Pro BDNF 抗体

The 兔 多克隆 anti-Pro BDNF antibody (ABIN350028) specifically detects Pro BDNF in IHC 和 WB. The antibody is reactive with 小鼠 samples.
产品编号 ABIN350028
发货至: 中国
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Quick Overview for Pro BDNF 抗体 (ABIN350028)

抗原

Pro BDNF (proBDNF) (Pro-Brain-Derived Neurotrophic Factor (proBDNF))

适用

  • 4
  • 1
小鼠

宿主

  • 2
  • 1
  • 1
  • 1

克隆类型

  • 4
  • 1
多克隆

标记

  • 4
  • 1
This Pro BDNF antibody is un-conjugated

应用范围

  • 5
  • 3
  • 3
  • 1
  • 1
  • 1
Immunohistochemistry (IHC), Western Blotting (WB)
  • 原理

    Rabbit antibody to proBDNF

    特异性

    Specific for proBDNF.

    交叉反应

    人, 小鼠, 大鼠

    交叉反应 (详细)

    Other species not yet tested.

    纯化方法

    IgG

    免疫原

    A synthetic peptide from mouse pro BDNF conjugated to blue carrier protein was used as the antigen.

    亚型

    IgG
  • 应用备注

    IHC WB. A concentration 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.

    注意事项

    Avoid freeze and thaw cycles.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

    有效期

    12 months
  • 抗原

    Pro BDNF (proBDNF) (Pro-Brain-Derived Neurotrophic Factor (proBDNF))

    别名

    proBDNF

    背景

    FUNCTION: Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP) long-term depression (LTD) certain forms of short-term synaptic plasticity as well as homeostatic regulation of intrinsic neuronal excitability. SUBUNIT: Monomers and homodimers. Binds to NTRK2/TRKB. SUBCELLULAR LOCATION: Secreted.

    UniProt

    P21237
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