ATG7 抗体 (C-Term)
Quick Overview for ATG7 抗体 (C-Term) (ABIN349977)
抗原
See all ATG7 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- C-Term
-
原理
- Sheep antibody to ATG7
-
特异性
- Specific for ATG7.
-
交叉反应
- 人, 小鼠, 大鼠
-
交叉反应 （详细）
- Other species not yet tested.
-
纯化方法
- IgG
-
免疫原
- A synthetic peptide from c-terminal region of human ATG7 conjugated to blue carrier protein has been used as the antigen. The peptide is homologous in rat and mouse.
-
亚型
- IgG
-
-
anti-ATG7 Autophagy Related 7 (ATG7) (AA 500-676) antibody
ATG7 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-ATG7 Autophagy Related 7 (ATG7) (AA 477-698) antibodyATG7 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-ATG7 Autophagy Related 7 (ATG7) (AA 540-569), (C-Term) antibodyATG7 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB7474 unconjugated
anti-ATG7 Autophagy Related 7 (ATG7) (AA 22-51) antibodyATG7 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-ATG7 Autophagy Related 7 (ATG7) (AA 494-523) antibodyATG7 适用: 人, 小鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-ATG7 Autophagy Related 7 (ATG7) antibodyATG7 适用: 人 WB, IHC, IP 宿主: 兔 Monoclonal unconjugated
anti-ATG7 Autophagy Related 7 (ATG7) (AA 558-703) antibodyATG7 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 7D3E5 unconjugated
anti-ATG7 Autophagy Related 7 (ATG7) (N-Term) antibodyATG7 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-ATG7 Autophagy Related 7 (ATG7) (N-Term) antibody (HRP)ATG7 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal HRP
anti-ATG7 Autophagy Related 7 (ATG7) (N-Term) antibody (FITC)ATG7 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal FITC
-
-
应用备注
- IHC WB. Use at a concentration of 10-50 μg,ml. The optimal working concentration should be determined by the end user. Not yet tested in other applications.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.
-
注意事项
- Avoid freeze and thaw cycles.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
-
有效期
- 12 months
-
-
- ATG7 (ATG7 Autophagy Related 7 (ATG7))
-
别名
- ATG7
-
背景
- This gene was identified based on homology to Pichia pastoris GSA7 and Saccharomyces cerevisiae APG7. In the yeast the protein appears to be required for fusion of peroxisomal and vaculuolar membranes. The protein shows homlogy to the ATP-binding and catalytic sites of the E1 ubiquitin activating enzymes. FUNCTION: Functions as an E1 enzyme essential for multisubstrates such as GABARAPL1 and ATG12. Forms intermediate conjugates with GABARAPL1 (GABARAPL2 GABARAP or MAP1ALC3). Formation of the final GABARAPL1-PE conjugate is essential for autophagy. SUBUNIT: Homodimer. Interacts with ATG3 and ATG12. The complex composed of ATG3 and ATG7 plays a role in the conjugation of ATG12 to ATG5. SUBCELLULAR LOCATION: Cytoplasm. TISSUE SPECIFICITY: Widely expressed especially in kidney liver lymph nodes and bone marrow. DOMAIN: The C-terminal part of the protein is essential for the dimerization and interaction with ATG3 and ATG12.
-
UniProt
- O95352
-
途径
- Response to Water Deprivation, Autophagy
抗原
-
