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AMBRA1 抗体 (N-Term)

This anti-AMBRA1 antibody is a 兔 多克隆 antibody detecting AMBRA1 in WB, IHC, ELISA 和 IP. Suitable for 人, 小鼠 和 大鼠. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN347117
发货至: 中国

Quick Overview for AMBRA1 抗体 (N-Term) (ABIN347117)

抗原

See all AMBRA1 抗体
AMBRA1 (Autophagy/beclin-1 Regulator 1 (AMBRA1))

适用

  • 40
  • 28
  • 12
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 54
  • 1

克隆类型

  • 54
  • 1
多克隆

标记

  • 16
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This AMBRA1 antibody is un-conjugated

应用范围

  • 46
  • 13
  • 13
  • 12
  • 10
  • 10
  • 10
  • 7
  • 3
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)
  • 抗原表位

    • 20
    • 15
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    特异性

    Reacts with mouse 120 kDa Ambra1 protein

    交叉反应

    大鼠

    交叉反应 (详细)

    Cross reacts with human and rat protein.

    纯化方法

    Antiserum

    免疫原

    Synthetic peptide derived from N-term domain of the mouse Ambra 1 protein.

    亚型

    IgG
  • 应用备注

    Working dilution: Optimal dilution should be determined by the end user.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Must be reconstituted in distilled water.

    储存条件

    4 °C/-20 °C

    储存方法

    Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

    有效期

    24 months
  • Armstrong, Corazzari, Martin, Pagliarini, Falasca, Hill, Ellis, Al Sabah, Redfern, Fimia, Piacentini, Lovat: "Oncogenic B-RAF signaling in melanoma impairs the therapeutic advantage of autophagy inhibition." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 17, Issue 8, pp. 2216-26, (2011) (PubMed).

    Di Bartolomeo, Corazzari, Nazio, Oliverio, Lisi, Antonioli, Pagliarini, Matteoni, Fuoco, Giunta, DAmelio, Nardacci, Romagnoli, Piacentini, Cecconi, Fimia: "The dynamic interaction of AMBRA1 with the dynein motor complex regulates mammalian autophagy." in: The Journal of cell biology, Vol. 191, Issue 1, pp. 155-68, (2010) (PubMed).

  • 抗原

    AMBRA1 (Autophagy/beclin-1 Regulator 1 (AMBRA1))

    别名

    Activating Molecule in BECN1-Regulated Autophagy Protein 1 (Ambra1)

    背景

    Regulates autophagy and development of the nervous system. Involved in autophagy in controlling protein turnover during neuronal development, and in regulating normal cell survival and proliferation

    基因ID

    55626

    UniProt

    Q9C0C7

    途径

    Autophagy
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