HMGB1 抗体 (meLys42, N-Term)
Quick Overview for HMGB1 抗体 (meLys42, N-Term) (ABIN347109)
抗原
See all HMGB1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- meLys42, N-Term
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特异性
- Reacts with HMGB1 methylated on Lysine 42 from human neutrophils
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交叉反应 (详细)
- Not tested in other species. May cross react with a wide range of species due to sequence homology.
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纯化方法
- Antiserum
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免疫原
- Synthetic peptide derived from N terminal region of HMGB1, containing mono-methyl at K42
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亚型
- IgG
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应用备注
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Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
IHC1:100 - 1:1000 WB1:200 -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Must be reconstituted in distilled water.
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储存条件
- 4 °C/-20 °C
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储存方法
- Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.
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有效期
- 24 months
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- HMGB1 (High Mobility Group Box 1 (HMGB1))
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别名
- HMGB1
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背景
- HMGB1 is a DAMP involved in innate immune response. It is secreted by activated dendritic cells, macrophages and necrotic cells.
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基因ID
- 3146
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UniProt
- P09429
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途径
- p53 Pathway, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Toll-Like Receptors Cascades, Smooth Muscle Cell Migration, Inflammasome
抗原
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