Ubinuclein 1 抗体 (AA 1-190)
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Quick Overview for Ubinuclein 1 抗体 (AA 1-190) (ABIN343714)
抗原
See all Ubinuclein 1 (UBN1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-190
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原理
- Anti-UBN1 Purified
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特异性
- The antibody UBN1-02 recognizes N-terminal part of ubinuclein 1 (UBN1), a widely expressed nuclear and adhesion complex protein. Western blotting analysis reveals UBN1 as a 165 kDa band.
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交叉反应 (详细)
- Human, Other species Not tested
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纯化方法
- Purified by protein-A affinity chromatography.
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纯度
- > 95 % (by SDS-PAGE)
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免疫原
- Recombinant protein corresponding to amino acids 1-190 of ubinuclein 1.
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亚型
- IgG1 kappa
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应用备注
- Western blotting: Recommended dilution: 1-5 μg/mL, positive control: HeLa cell line.
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Do not freeze.
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储存条件
- 4 °C
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储存方法
- Store at 2-8°C. Do not freeze.
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- Ubinuclein 1 (UBN1)
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别名
- UBN1
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背景
- Ubinuclein 1,Ubinuclein 1 (UBN1) is a ubiquitously expressed evolutionarily conserved protein which binds to proliferation-promoting genes that are repressed by formation of senescence-associated heterochromatin foci (SAHF). Ubinuclein 1 associates with various transcription factors and with histone methyltransferase activity, is indispensable for SAHF formation and appears to be a regulator of senescence. Although in most cells ubinuclein is localized to the nucleus, in cells forming tight junctions it is recruited to the cell adhesion complexes, dependently on the cell density.,Ubinuclein 1, VT4
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基因ID
- 29855
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UniProt
- Q6PIZ9
抗原
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