MTA2 抗体 (AA 652-668)
Quick Overview for MTA2 抗体 (AA 652-668) (ABIN342361)
抗原
See all MTA2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 652-668
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特异性
- Recognizes human, mouse, and rat PID/MTA2, a subunit of the nucleosome remodeling and deacetylating (NRD/NuRD) complex. PID/MTA2 modulates the enzymatic activity of the histone deacetylase complex, and its expression reduces the levels of acetylated p53. Deacetylation of p53 by PID/MTA2 represses p53- dependent transcriptional activation and modulates p53-mediated cell growth arrest and apoptosis. PID/MTA2 is expressed in a variety of tissues. Does not cross-react with MTA1.
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纯化方法
- Immunoaffinity purified
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免疫原
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Peptide corresponding to aa 652-668 of human PID/MTA2. This sequence differs from that of mouse by one amino acid.
Type of Immunogen: Synthetic peptide
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应用备注
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Approved: WB (0.5 - 1 μg/mL)
Usage: Western Blot: A band of 75 kD is detected. -
说明
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Target Species of Antibody: Human
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- PBS, pH 7.4, 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
- 4°C or -20°C, Avoid freeze-thaw cycles.
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- MTA2 (Metastasis Associated 1 Family, Member 2 (MTA2))
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别名
- MTA2
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背景
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Name/Gene ID: MTA2
Synonyms: MTA2, Metastasis-associated 1-like 1, MTA1L1, PID, MTA1-L1, MTA1-L1 protein -
基因ID
- 9219
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UniProt
- O94776
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途径
- Chromatin Binding
抗原
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