CCR6 抗体 (AA 18-46)
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Quick Overview for CCR6 抗体 (AA 18-46) (ABIN337207)
抗原
See all CCR6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 18-46
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特异性
- Recognizes human CCR6. Peptide sequence is <50 % identical to other human chemokine receptors in this region. Species cross-reactivity: mouse.
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预测反应
- Percent identity by BLAST analysis: Human, Gorilla, Gibbon (100%) Monkey (86%).
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纯化方法
- Immunoaffinity purified
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免疫原
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Synthetic peptide corresponding to aa 18-46 (Y18FVSVNTSYYSVDSEMLLCSLQEVRQFSR46) of human CCR6 (C-C chemokine receptor 6). Peptide sequence is <50% identical to other human chemokine receptors in this region. Percent identity by BLAST analysis: Human, Gorilla, Gibbon (100%), Monkey (86%).
Type of Immunogen: Synthetic peptide -
亚型
- IgG
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应用备注
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Approved: ELISA (1:75000), Flo (1 - 3 μg/10 x106), ICC (1:300), IHC, IHC-P (5 μg/mL)
Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 5 μg/mL. ELISA: 1:75000. Flow Cytometry: 50-100 μL, 1-3 μL per 10^6 cells. -
说明
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Target Species of Antibody: Human
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- PBS, 1 mg/mL BSA, 0.1 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
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- CCR6 (Chemokine (C-C Motif) Receptor 6 (CCR6))
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别名
- CCR6
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背景
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Name/Gene ID: CCR6
Subfamily: Chemokine
Family: GPCR
Synonyms: CCR6, C-c chemokine receptor 6, CD196 antigen, BN-1, C-C chemokine receptor type 6, C-C CKR-6, Chemokine c-c motif receptor 6, CKRL3, CMKBR6, Chemokine (C-C) receptor 6, Chemokine receptor-like 3, Cc chemokine receptor 6, CC-CKR-6, CCR-6, DCR2, DRY6, G protein-coupled receptor 29, DRY-6, G-protein coupled receptor 29, GPR29, GPRCY4, Strl-22, STRL22, CD196, CKR-L3, GPR-CY4, LARC receptor -
基因ID
- 1235
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UniProt
- P51684
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途径
- cAMP Metabolic Process
抗原
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