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FLIP 抗体 (N-Term)

This 小鼠 单克隆 antibody specifically detects FLIP in WB 和 EIA. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN336100
发货至: 中国
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Quick Overview for FLIP 抗体 (N-Term) (ABIN336100)

抗原

See all FLIP (CFLAR) 抗体
FLIP (CFLAR) (CASP8 and FADD-Like Apoptosis Regulator (CFLAR))

适用

  • 104
  • 67
  • 56
  • 2
  • 2
  • 2
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 96
  • 14
  • 2
小鼠

克隆类型

  • 98
  • 14
单克隆

标记

  • 58
  • 5
  • 5
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This FLIP antibody is un-conjugated

应用范围

  • 99
  • 39
  • 29
  • 26
  • 19
  • 18
  • 17
  • 14
  • 13
  • 10
  • 9
  • 4
  • 1
  • 1
  • 1
Western Blotting (WB), Enzyme Immunoassay (EIA)

克隆位点

5D8
  • 抗原表位

    • 16
    • 15
    • 15
    • 10
    • 8
    • 7
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-376, N-Term

    特异性

    The antibody recognizes FLIP.

    产品特性

    Synonyms: c-FLIP, CLARP, MRIT, CASH, FLAME-1, CASP8AP1, Usurpin, CASP8 and FADD-like apoptosisregulator, Caspase-eight-related protein, Inhibitor of FLICE, Cellular FLICE-like inhibitoryprotein, Caspase-like apoptosis regulatory protein, MACH-related inducer of toxicity,Caspase homolog, FADD-like antiapoptotic molecule 1

    纯化方法

    Affinity Chromatography on Protein G

    免疫原

    Recombinant human FLIP (aa 1-376) purified from E. coli.

    亚型

    IgG3
  • 应用备注

    ELISA. Western Blot (1/500-1/1000).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.0 mg/mL

    缓冲液

    PBS, pH 7.4, 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for up to two weeks or (in aliquots) at -20 °C or -70 °Cfor longer. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    FLIP (CFLAR) (CASP8 and FADD-Like Apoptosis Regulator (CFLAR))

    别名

    CFLAR / Casper / I-FLICE

    背景

    FLIP, also known as CASP8 and FADD-like apoptosis regulator (CFLAR), contains two death effector domains (DEDs) and a caspase-like domain. FLIP may play a crucial role between cell survival and cell death pathway in mammalian cells and interacts with adapter protein FADD and Caspase-8 and -10, and potently inhibits apoptosis induced by all known death receptors DR3 (Death Receptor 3), TRAIL-R (TNF-related apoptosis-inducing ligand receptor) and TNFR1 (Tumor Necrosis Factor Receptor 1).Synonyms: CASH, CASP8 and FADD-like apoptosis regulator, CASP8AP1, CLARP, Caspase homolog, Caspase-eight-related protein, Caspase-like apoptosis regulatory protein, Cellular FLICE-like inhibitory protein, FADD-like antiapoptotic molecule 1, FLAME-1, Inhibitor of FLICE, MACH-related inducer of toxicity, MRIT, Usurpin, c-FLIP

    基因ID

    8837

    UniProt

    O15519

    途径

    Apoptosis, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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