Lamin B1 抗体
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北京 101111
Quick Overview for Lamin B1 抗体 (ABIN335391)
抗原
See all Lamin B1 (LMNB1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Human, rat, mouse, bovine, rabbit, dog, sheep.
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纯化方法
- Purified
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免疫原
- 119D5-F1 is a mouse monoclonal IgG1/kappa antibody derived by fusion of P3/X63.Ag8.653 mouse myeloma cells with spleen cells from a BALB/c mouse immunized with purified rat liver lamins.
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亚型
- IgG1
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anti-Lamin B1 (LMNB1) (AA 397-586) antibody
LMNB1 适用: 人 WB, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Lamin B1 (LMNB1) (AA 266-583) antibodyLMNB1 适用: 人, 小鼠, 大鼠 WB, IHC, IP, ICC, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-Lamin B1 (LMNB1) (AA 52-233) antibodyLMNB1 适用: 人 WB 宿主: 小鼠 Monoclonal C2 unconjugated
anti-Lamin B1 (LMNB1) (AA 107-186) antibodyLMNB1 适用: 人 WB, ELISA, IP, IF 宿主: 小鼠 Monoclonal 4B10 unconjugated
anti-Lamin B1 (LMNB1) (AA 107-186) antibodyLMNB1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 4E4 unconjugated
anti-Lamin B1 (LMNB1) (AA 570-586), (C-Term) antibodyLMNB1 适用: 人, 小鼠, 大鼠 WB, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Lamin B1 (LMNB1) (AA 570-586) antibodyLMNB1 适用: 人, 大鼠 WB, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Lamin B1 (LMNB1) antibodyLMNB1 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Lamin B1 (LMNB1) antibodyKO Validated LMNB1 适用: 人 WB, IP, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Lamin B1 (LMNB1) antibodyLMNB1 适用: 人, 小鼠, 大鼠 WB, IP, IF, IHC (p) 宿主: 小鼠 Monoclonal 4K2 unconjugated
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应用备注
- 119D5-F1 reacts with an epitope located C-terminal of residue 231 in lamin B1. 119D5-F1 is suitable for immunocytochemistry, immunoblotting, ELISA and flow cytometry. Optimal antibody dilution should be determined by titration, recommended range is 1:100 - 1:200 for flow cytometry, and for immunocytochemistry with avidin-biotinylated horseradish peroxidase complex (ABC) as detection reagent, and 1:100 - 1:1000 for immunoblotting applications.
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限制
- 仅限研究用
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储存条件
- 4 °C
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: "Nuclear lamins: laminopathies and their role in premature ageing." in: Physiological reviews, Vol. 86, Issue 3, pp. 967-1008, (2006) (PubMed).
: "Partial cleavage of A-type lamins concurs with their total disintegration from the nuclear lamina during apoptosis." in: European journal of cell biology, Vol. 81, Issue 12, pp. 677-91, (2003) (PubMed).
: "Lamin A is part of the internal nucleoskeleton of human erythroleukemia cells." in: Journal of cellular physiology, Vol. 178, Issue 3, pp. 284-95, (1999) (PubMed).
: "Distinct nuclear assembly pathways for lamins A and C lead to their increase during quiescence in Swiss 3T3 cells." in: Journal of cell science, Vol. 110 ( Pt 19), pp. 2483-93, (1997) (PubMed).
: "A- and B-type lamins are differentially expressed in normal human tissues." in: Histochemistry and cell biology, Vol. 107, Issue 6, pp. 505-17, (1997) (PubMed).
: "Comparison of A and B-type lamin expression in reactive lymph nodes and nodular sclerosing Hodgkin's disease." in: Histopathology, Vol. 31, Issue 4, pp. 304-12, (1997) (PubMed).
: "Nuclear lamin expression in normal testis and testicular germ cell tumours of adolescents and adults." in: The Journal of pathology, Vol. 182, Issue 2, pp. 197-204, (1997) (PubMed).
: "Abnormal A-type lamin organization in a human lung carcinoma cell line." in: European journal of cell biology, Vol. 67, Issue 4, pp. 328-35, (1996) (PubMed).
: "Degradation of nuclear matrix and DNA cleavage in apoptotic thymocytes." in: Journal of cell science, Vol. 109 ( Pt 1), pp. 45-56, (1996) (PubMed).
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: "Nuclear lamins: laminopathies and their role in premature ageing." in: Physiological reviews, Vol. 86, Issue 3, pp. 967-1008, (2006) (PubMed).
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- Lamin B1 (LMNB1)
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别名
- Lamin B1
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背景
- Nuclear lamins form a network of intermediate-type filaments at the nucleoplasmic site of the nuclear membrane. Two main subtypes of nuclear lamins can be distinguished, i.e. A-type lamins and B-type lamins. The A-type lamins comprise a set of three proteins arising from the same gene by alternative splicing, i.e. lamin A, lamin C and lamin Adel 10, while the B-type lamins include two proteins arising from two distinct genes, i.e. lamin B1 and lamin B2.
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途径
- Apoptosis, Caspase Cascade in Apoptosis
抗原
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