PARK7/DJ1 抗体
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北京 101111
Quick Overview for PARK7/DJ1 抗体 (ABIN335354)
抗原
See all PARK7/DJ1 (PARK7) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Human, mouse, dog and Xenopus laevis.
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纯化方法
- Serum
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免疫原
- 12B11F8 is a mouse monoclonal IgG1 antibody derived by fusion of mouse myeloma cells with spleen cells from a mouse immunized with a synthetic peptide corresponding to amino acid residues 779-793 of human plakophilin-3 coupled to keyhole limpet hemocyanin. (KLHRDFRAKGYRKED).
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亚型
- IgG1
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anti-Parkinson Protein 7 (PARK7) (AA 1-189) antibody
PARK7 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Parkinson Protein 7 (PARK7) (C-Term) antibodyVerified PARK7 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-Parkinson Protein 7 (PARK7) (AA 101-189) antibodyPARK7 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Parkinson Protein 7 (PARK7) (C-Term) antibodyPARK7 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Parkinson Protein 7 (PARK7) (AA 2-189) antibodyPARK7 适用: 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Parkinson Protein 7 (PARK7) (AA 1-188) antibodyPARK7 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Parkinson Protein 7 (PARK7) (AA 1-189) antibodyPARK7 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Parkinson Protein 7 (PARK7) (AA 2-189) antibodyPARK7 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Parkinson Protein 7 (PARK7) (AA 1-189) antibodyPARK7 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Parkinson Protein 7 (PARK7) (AA 130-164), (C-Term) antibodyPARK7 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB49681 unconjugated
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应用备注
- 12B11F8 reacts with an epitope located between residues 779-793 in human plakophilin-3. 12B11F8 is suitable for immunocytochemistry (methanol-fixed cells), immunohistochemistry on frozen tissues, immunoprecipitation and Western blot detection. For optimal results, fixed cells or tissues should be treated with 0.2% Triton-X 100 for 5 min. prior to incubation with primary antibody. Optimal antibody dilution should be determined by titration, recommended range is 1:25 - 1:200 for immunohistochemistry with avidin-biotinylated horseradish peroxidase complex (ABC) as detection reagent, and 1:100 - 1:1000 for immunoblotting applications.
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限制
- 仅限研究用
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储存条件
- 4 °C
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: "Defining desmosomal plakophilin-3 interactions." in: The Journal of cell biology, Vol. 161, Issue 2, pp. 403-16, (2003) (PubMed).
: "Plakophilin-3, a novel armadillo-like protein present in nuclei and desmosomes of epithelial cells." in: Journal of cell science, Vol. 112 ( Pt 14), pp. 2265-76, (1999) (PubMed).
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: "Defining desmosomal plakophilin-3 interactions." in: The Journal of cell biology, Vol. 161, Issue 2, pp. 403-16, (2003) (PubMed).
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- PARK7/DJ1 (PARK7) (Parkinson Protein 7 (PARK7))
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别名
- PARK7 / DJ-1
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背景
- Plakophilin-3 is an Armadillo-like protein present in nuclei and desmosomes of epithelial cells [1]. The expression pattern of this protein seems to be largely restricted to epithelial cell types. Plakophilin-3 can be detected along cell borders in a punctuate staining pattern typical for desmosomal proteins. In addition to the desmosomal immunolocalisation, immunostaining was observed as bright nuclear speckles. Thus, like plakophilin-1 and-2, plakophilin-3 displays a dual intracellular localisation in the desmosomal plaque and in the cell nucleus, and therefore is probably involved in signal transduction pathways between the plasma membrane and the nucleus. The human protein has a predicted molecular mass of 87 kD.
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Proton Transport
抗原
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