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Keratin 10 抗体

KRT10 适用: 人, 犬, Cat FACS, WB, IHC, IHC (p), ICC, IHC (fro) 宿主: 小鼠 Monoclonal DE-K10 unconjugated
产品编号 ABIN335337
发货至: 中国
  • 抗原 See all Keratin 10 (KRT10) 抗体
    Keratin 10 (KRT10)
    适用
    • 120
    • 57
    • 50
    • 26
    • 17
    • 5
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    人, 犬, Cat
    宿主
    • 75
    • 48
    • 2
    小鼠
    克隆类型
    • 67
    • 58
    单克隆
    标记
    • 71
    • 10
    • 5
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    This Keratin 10 antibody is un-conjugated
    应用范围
    • 79
    • 55
    • 52
    • 39
    • 34
    • 26
    • 14
    • 14
    • 13
    • 11
    • 10
    • 8
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    Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    Human, feline and canine.
    纯化方法
    Purified
    免疫原
    DE-K10 is a mouse monoclonal IgG1, kappa antibody derived by fusion of SP2/0 mouse myeloma cells with spleen cells from a (BALB/c x B6)F1 mouse immunized with a cytoskeletal preparation extracted from human epidermis.
    克隆位点
    DE-K10
    亚型
    IgG1
    Top Product
    Discover our top product KRT10 Primary Antibody
  • 应用备注
    DE-K10 reacts exclusively with cytokeratin 10 which is present in keratinizing stratified epithelia and in differentiated areas of highly differentiated squamous cell carcinomas. DE-K10 is useful for immunocytochemistry, immunohistochemistry on frozen and paraffin-embedded tissues, immunoblotting and flow cytometry. Optimal antibody dilution should be determined by titration, recommended range is 1:100 - 1:200 for flow cytometry, and for immunohistochemistry with avidin-biotinylated horseradish peroxidase complex (ABC) as detection reagent, and 1:100 - 1:1000 for immunoblotting applications.
    限制
    仅限研究用
  • 储存条件
    4 °C
  • Stout, Westdijk, Calkhoven, Pijper, Backendorf, Willemze, Mullenders, de Gruijl: "Epidermal transit of replication-arrested, undifferentiated keratinocytes in UV-exposed XPC mice: an alternative to in situ apoptosis." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, Issue 52, pp. 18980-5, (2005) (PubMed).

    van Bommel, Kenemans, Helmerhorst, Gallee, Ivanyi: "Expression of cytokeratin 10, 13, and involucrin as prognostic factors in low stage squamous cell carcinoma of the uterine cervix." in: Cancer, Vol. 74, Issue 8, pp. 2314-20, (1994) (PubMed).

    Vos, van den Ingh, de Neijs, van Mil, Ivanyi, Ramaekers: "Immunohistochemistry with keratin monoclonal antibodies in canine tissues: urogenital tract, respiratory tract, (neuro-)endocrine tissues, choroid plexus and spinal cord." in: Zentralblatt für Veterinärmedizin. Reihe A, Vol. 39, Issue 10, pp. 721-40, (1993) (PubMed).

    Ivanyi, Minke, Hageman, Groeneveld, van Doornewaard, Misdorp: "Cytokeratins as markers of initial stages of squamous metaplasia in feline mammary carcinomas." in: American journal of veterinary research, Vol. 54, Issue 7, pp. 1095-102, (1993) (PubMed).

    Vos, van den Ingh, Ramaekers, Molenbeek, de Neijs, van Mil, Ivanyi: "The expression of keratins, vimentin, neurofilament proteins, smooth muscle actin, neuron-specific enolase, and synaptophysin in tumors of the specific glands in the canine anal region." in: Veterinary pathology, Vol. 30, Issue 4, pp. 352-61, (1993) (PubMed).

    Ivanyi, Minke, Hageman, Groeneveld, van Doornewaard: "Patterns of expression of feline cytokeratins in healthy epithelia and mammary carcinoma cells." in: American journal of veterinary research, Vol. 53, Issue 3, pp. 304-14, (1992) (PubMed).

    Ivanyi, Groeneveld, Van Doornewaard, Mooi, Hageman: "Keratin subtypes in carcinomas of the uterine cervix: implications for histogenesis and differential diagnosis." in: Cancer research, Vol. 50, Issue 16, pp. 5143-52, (1990) (PubMed).

    Ivanyi, Ansink, Mooi, de Kraker, Heintz: "Absence of differentiation-related expression of keratin 10 in early stages of vulvar squamous carcinoma." in: Differentiation; research in biological diversity, Vol. 42, Issue 2, pp. 124-9, (1990) (PubMed).

    Ivanyi, Ansink, Groeneveld, Hageman, Mooi, Heintz: "New monoclonal antibodies recognizing epidermal differentiation-associated keratins in formalin-fixed, paraffin-embedded tissue. Keratin 10 expression in carcinoma of the vulva." in: The Journal of pathology, Vol. 159, Issue 1, pp. 7-12, (1989) (PubMed).

  • 抗原
    Keratin 10 (KRT10)
    别名
    Cytokeratin 10 / Keratin K10 (KRT10 产品)
    别名
    BCIE antibody, BIE antibody, CK10 antibody, EHK antibody, K10 antibody, KPP antibody, D130054E02Rik antibody, K1C1 antibody, Krt-1.10 antibody, Krt1-10 antibody, Ka10 antibody, Ker10 antibody, KRT10 antibody, KRT25 antibody, KRT27 antibody, KRT28 antibody, keratin 10 antibody, keratin 10, type I S homeolog antibody, keratin, type I cytoskeletal 25 antibody, KRT10 antibody, Krt10 antibody, krt10.S antibody, LOC101085587 antibody
    背景
    Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. They range in molecular weight between 40 kDa and 68 kDa and isoelectric pH between 4.9 - 7.8. The individual human cytokeratins are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays.
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