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Amylin/DAP 抗体

This anti-Amylin/DAP antibody is a 小鸡 多克隆 antibody detecting Amylin/DAP in WB 和 ELISA. Suitable for 人.
产品编号 ABIN334637
发货至: 中国

Quick Overview for Amylin/DAP 抗体 (ABIN334637)

抗原

See all Amylin/DAP (IAPP) 抗体
Amylin/DAP (IAPP) (Islet Amyloid Polypeptide (IAPP))

适用

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宿主

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小鸡

克隆类型

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多克隆

标记

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This Amylin/DAP antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 产品特性

    Expected / apparent Molecular Weight of the Antigene: 4 kDa

    纯化方法

    affinity purified

    免疫原

    synthetic peptide based on human IAPP sequence: K-C-N-T-A-T-C-A-T-Q-R-L-A-N-F-L-V-H-S-S-N-N-F-G-A-I-L-S-S-T-N-V-G-S-N-T-Y

    亚型

    IgY
  • 应用备注

    Recommended Dilution: 1 : 1000 (WB), 1 : 1000 (ELISA).

    说明

    antibody is recognizing trimer, dimer and monomer human IAPP

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS pH 8.0 + 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from liquid material adhering to the cap or sides of the tubes.
    Make aliquots to avoid repreated freeze-thaw cycles and working with a stock.

    储存条件

    4 °C
  • 抗原

    Amylin/DAP (IAPP) (Islet Amyloid Polypeptide (IAPP))

    别名

    IAPP

    背景

    Amylin, or Islet Amyloid Polypeptide (IAPP) P10997, is a 37-residue peptide hormone secreted by pancreatic beta-cells at the same time as insulin (in a roughly 1:100 amylin:insulin ratio). Islet, or insulinoma, almyloid polypeptide (IAPP, or amylin) is commonly found in pancreatic islets of patients suffering diabetes mellitus type 2, or harboring an insulinoma. While the association of amylin with the development of type 2 diabetes has been known for some time, a direct causative role for amylin has been harder to establish. Recent results suggest that amylin, like the related beta-amyloid (Abeta) associated with Alzherimer's disease, can induce apoptotic cell-death in particular cultured cells, an effect that may be relevant to the deleopment of type 2 diabetes.

    分子量

    4 kDa

    途径

    Hormone Activity, Feeding Behaviour
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