Amylin/DAP 抗体 (AA 2-7)
Our Local Distributor
北京 101111
Quick Overview for Amylin/DAP 抗体 (AA 2-7) (ABIN334637)
抗原
See all Amylin/DAP (IAPP) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 2-7
-
原理
- Anti-IAPP | Human IAPP (amylin) 1-37, specific for the native hormone having a disulphide-bridge between Cys2-Cys7
-
交叉反应 （详细）
-
Human
Not reactive in: No confirmed exceptions from predicted reactivity are currently known -
预测反应
- Primates,mouse,rat,dog,seal,Chinese hamster
-
纯化方法
- Purified,total IgY
-
免疫原
- Synthetic peptide corresponding to the human the 37 residue IAPP also known as amylin. The IAPP/amylin peptide contains a disulphide-bridge between Cys2-Cys7 Amino acid sequence: KCNTATCATQRLANFLVHSSNNFGAILSSTNVGSNTY (disulphide link between Cys2-Cys7)
-
亚型
- IgY
-
-
anti-Islet Amyloid Polypeptide (IAPP) antibody
IAPP 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal C2 unconjugated
anti-Islet Amyloid Polypeptide (IAPP) (Internal Region) antibodyIAPP 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Islet Amyloid Polypeptide (IAPP) (AA 34-70) antibodyIAPP 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Islet Amyloid Polypeptide (IAPP) (AA 1-89) antibodyIAPP 适用: 人 宿主: 兔 Polyclonal unconjugated
anti-Islet Amyloid Polypeptide (IAPP) (N-Term) antibodyIAPP 适用: 人, 兔, 犬, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Islet Amyloid Polypeptide (IAPP) antibodyIAPP 适用: 人 IF, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal R10-99 unconjugated
anti-Islet Amyloid Polypeptide (IAPP) (N-Term) antibodyIAPP 适用: 人, 大鼠, 小鼠, 兔 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Islet Amyloid Polypeptide (IAPP) antibodyIAPP 适用: 人, 大鼠, 小鼠 WB, IHC (p), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Islet Amyloid Polypeptide (IAPP) (N-Term) antibodyIAPP 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Islet Amyloid Polypeptide (IAPP) (AA 10-90) antibodyIAPP 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- 1:1000 (WB), 1:1000 (ELISA)
-
说明
-
antibody is recognizing trimer, dimer and monomer human IAPP
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
缓冲液
- Purified,total IgY (chicken egg yolk immunoglobulin) in PBS pH 8. Contains 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube
-
储存条件
- -20 °C
-
储存方法
- Store lyophilized/reconstituted at -20°C, once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.
-
-
- Amylin/DAP (IAPP) (Islet Amyloid Polypeptide (IAPP))
-
别名
- IAPP
-
背景
- Amylin, or Islet Amyloid Polypeptide (IAPP) P10997, is a 37-residue peptide hormone secreted by pancreatic beta-cells at the same time as insulin (in a roughly 1:100 amylin:insulin ratio). Islet, or insulinoma, almyloid polypeptide (IAPP, or amylin) is commonly found in pancreatic islets of patients suffering diabetes mellitus type 2, or harboring an insulinoma. While the association of amylin with the development of type 2 diabetes has been known for some time, a direct causative role for amylin has been harder to establish. Recent results suggest that amylin, like the related beta-amyloid (Abeta) associated with Alzherimer's disease, can induce apoptotic cell-death in particular cultured cells, an effect that may be relevant to the deleopment of type 2 diabetes.
-
分子量
- 3.9 kDa
-
途径
- Hormone Activity, Feeding Behaviour
抗原
-
