Mesothelin 抗体
Quick Overview for Mesothelin 抗体 (ABIN328471)
抗原
See all Mesothelin (MSLN) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Recognizes human mesothelin. This antibody binds to mesothelin cleaved form which is the ~40 kDa cell membrane-associated glycosylphosphatidylinositol-linked glycoprotein. It is not expected to react with the soluble portion of the mesothelin precursor protein that is designated as the megakaryocyte potentiating factor.
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纯化方法
- Immunoaffinity purified
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免疫原
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NS0-derived recombinant human mesothelin.
Type of Immunogen: Recombinant protein -
亚型
- IgG2a
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应用备注
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Approved: ELISA (0.5 - 1 μg/mL), Flo (2.5 μg/10 x106)
Usage: Flow Cytometry: This antibody was validated for flow cytometry using Hela human cervical carcinoma cells. Use at 2.5 μg per 10e6 cells. Direct ELISA: 0.5-1.0 μg/mL with the appropriate secondary reagents to detect human Mesothelin. The detection limit for rhMesothelin is approximately 5 ng/well. -
说明
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Target Species of Antibody: Human
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- 200 μL sterile PBS
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浓度
- Lot specific
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缓冲液
- Lyophilized from PBS, pH 7.4, 5 % trehalose
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注意事项
- Avoid freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze-thaw cycles.
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- Mesothelin (MSLN)
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别名
- MSLN / Mesothelin
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背景
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Name/Gene ID: MSLN
Synonyms: MSLN, CAK1 antigen, MPF, SMRP, Mesothelin, CAK1 -
基因ID
- 10232
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途径
- EGFR Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Carbohydrate Homeostasis, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process
抗原
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