BACE1 抗体
Quick Overview for BACE1 抗体 (ABIN325261)
抗原
See all BACE1 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Recognizes human BACE-1 ectodomain. Species cross-reactivity: Mouse.
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纯化方法
- Protein G purified
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免疫原
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NS0-derived rhBACE-1 ectodomain.
Type of Immunogen: Recombinant protein -
亚型
- IgG1
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anti-Beta-secretase 1 (BACE1) (AA 22-501) antibody
BACE1 适用: 人 WB, ELISA, IHC (p), PLA 宿主: 小鼠 Monoclonal 2C1 unconjugated
anti-Beta-secretase 1 (BACE1) (AA 112-324) antibodyBACE1 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 3C1C3 unconjugated
anti-Beta-secretase 1 (BACE1) (N-Term) antibodyBACE1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Beta-secretase 1 (BACE1) (AA 401-501) antibodyBACE1 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC, IHC (p), FACS, IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Beta-secretase 1 (BACE1) (AA 22-322) antibodyBACE1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Beta-secretase 1 (BACE1) (AA 46-155) antibodyBACE1 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Beta-secretase 1 (BACE1) (AA 72-121) antibodyBACE1 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 兔, 猴, Pig, Bat, Hamster WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Beta-secretase 1 (BACE1) (C-Term) antibodyBACE1 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Beta-secretase 1 (BACE1) (N-Term) antibodyBACE1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Beta-secretase 1 (BACE1) (AA 38-70), (N-Term) antibodyBACE1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB16874 unconjugated
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应用备注
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Approved: ELISA, IP, Neut, WB
Usage: Suitable for use in ELISA, Immunoprecipitation/ Western Blot and Neutralization. The enzyme was then assayed with a peptide substrate. 50 % of the proteolytic activity was inhibited by the antibody at 10 μg/mL (IC50) under conditions in which the enzyme was present at 10 μg/mL and the substrate concentration was 10uM. Considering the molecular masses of the enzyme (75kD) and the antibody (150kD), IC50 was achieved at ~0.5:1 Molar ratio of the antibody to the enzyme. Did not inhibit rhCathepsin D activity under the same conditions. -
说明
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Target Species of Antibody: Human
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Sterile PBS
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浓度
- Lot specific
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缓冲液
- Lyophilized, PBS, pH 7.4, 5 % trehalose
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
- 4°C or -20°C, Avoid freeze-thaw cycles.
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- BACE1 (Beta-secretase 1 (BACE1))
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别名
- BACE1 / BACE
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背景
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Name/Gene ID: BACE1
Subfamily: Aspartic A1
Family: Protease
Synonyms: BACE1, APP beta-secretase, Asp 2, ASP2, Aspartyl protease 2, Aspartylprotease 2, Beta-secretase, Beta-site APP-cleaving enzyme, BACE, HSPC104, KIAA1149, B-Secretase, Beta-secretase 1, Memapsin-2 -
基因ID
- 23621
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UniProt
- P56817
抗原
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