P-Selectin 抗体 (PE)
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Quick Overview for P-Selectin 抗体 (PE) (ABIN320270)
抗原
See all P-Selectin (SELP) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody recognises the CD62P cell surface antigen, a 140 kDa glycoprotein also known as P-selectin. Clone Psel.KO.2.12 is reported to inhibit P-selectin-dependent adhesion between HL60 cells and P-selectin transfected COS cells. We recommend the use of Azide Free, Low Endotoxin CD62P antibody Cat.-No SM2262LE for this purpose.Cat.-No
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纯化方法
- Affinity Chromatography on Protein G
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免疫原
- CD62P transfected 300.19 cells. Spleen cells from immunised CD62P knock-out mice (Strain C57/B6) were fused with cells of the NS-1 myeloma cell line.
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亚型
- IgG1
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anti-Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP) (AA 701-768) antibody
SELP 适用: 人, 大鼠, 小鼠, Pig WB, FACS, ELISA, IHC (fro), IHC (p), IF (p), IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP) (AA 198-432) antibodySELP 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP) (AA 58-158) antibodySELP 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP) (AA 30-200) antibodySELP 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP) antibodySELP 适用: 人, Non-Human Primate WB, FACS, IP, ICC, IHC (fro) 宿主: 小鼠 Monoclonal AK4 unconjugated
anti-Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP) (AA 58-195) antibodySELP 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP) (AA 198-432) antibodySELP 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C18 unconjugated
anti-Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP) antibodySELP 适用: 人 WB, IHC, IP 宿主: 兔 Monoclonal unconjugated
anti-Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP) antibodySELP 适用: 人, Non-Human Primate WB, FACS, IP, ICC, IHC (fro), Func 宿主: 小鼠 Monoclonal AK4 unconjugated
anti-Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP) antibody (Biotin)SELP 适用: 人, Non-Human Primate WB, FACS, IP, ICC, IHC (fro) 宿主: 小鼠 Monoclonal AK4 Biotin
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应用备注
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Flow Cytometry (Neat).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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溶解方式
- Restore with 1.0 mL distilled water
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.09 % Sodium Azide, 1 % BSA and 5 % Sucrose
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in alqiuots) at -20 °C for longer.
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- P-Selectin (SELP) (Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP))
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别名
- CD62P / P-Selectin
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背景
- CD62P is a member of the small selectin family of cellular adhesion molecules, which also includes CD62E and CD62L. Its structure, similar to the other members of the selectin family, consists of an N terminal lectin like domain of C type, followed by an epidermal growth factor like motif, a series of short consensus repeats, a transmembrane domain, and a cytoplasmic tail. The CD62P antigen is a 140 kDa glycoprotein, located in the alpha granules and the dense granules of platelets and endothelial cells. Activation of these cells results in rapid mobilization of CD62P from the storage granules to the cell surface. Activated platelets have a stable CD62P expression, while the endothelial cells lose CD62P expression within 1 h of activation, because of endocytosis of the molecule. CD62P is also expressed on megakaryocytes, but resting platelets and endothelial cells show no surface staining of CD62P.Synonyms: CD62 antigen-like family member P, GMP-140, GMRP, GRMP, Granule membrane protein 140, LECAM3, Leukocyte-endothelial cell adhesion molecule 3, PADGEM, SELP
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基因ID
- 6403
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NCBI登录号
- NP_002996
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UniProt
- P16109
抗原
-
