P-Selectin 抗体 (PE)
Quick Overview for P-Selectin 抗体 (PE) (ABIN320268)
抗原
See all P-Selectin (SELP) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody recognises the CD62P cell surface antigen, a 140 kDa glycoprotein also known as P-Selectin.
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产品特性
- Absorption / Emission: 488nm / 575nm
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纯化方法
- Affinity Chromatography on Protein G.
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免疫原
- P-selectin transfected 300.19 cells.
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亚型
- IgG1
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应用备注
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Flow Cytometry: Use 10 μL of Neat-1/5 diluted antibody to label 106 cells in 100 μL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- approx. 0.1 mg/mL
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缓冲液
- PBS, 0.09 % Sodium Azide, 1 % BSA, 5 % Sucrose
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- This product is photosensitive and should be protected from light
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!
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- P-Selectin (SELP) (Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP))
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别名
- CD62P / P-Selectin
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背景
- CD62P (P-selectin) is an adhesion glycoprotein that is expressed on platelets and endothelial cells upon their activation. Interaction between CD62P and its mucin-like ligand PSGL-1 (P-selectin glycoprotein ligand-1) expressed on the microvilli of most leukocytes supports leukocyte rolling along postkapillary venules at the earliest time of inflammation. Both CD62P and PSGL-1 are extended glycoproteins that form homodimers. CD62P dimerization is probably mediated through interactions of the transmembrane domains and stabilizes leukocyte tethering and rolling, probably by increasing rebinding within a bond clusterSynonyms: CD62 antigen-like family member P, GMP-140, GMRP, GRMP, Granule membrane protein 140, LECAM3, Leukocyte-endothelial cell adhesion molecule 3, PADGEM, SELP
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基因ID
- 6403
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NCBI登录号
- NP_002996
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UniProt
- P16109
抗原
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