KDM5A 抗体 (AA 1416-1434)
Quick Overview for KDM5A 抗体 (AA 1416-1434) (ABIN3201015)
抗原
See all KDM5A 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1416-1434
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特异性
- Specific to human and mouse RBP2. Can detect endogenous levels of RBP2.
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纯化方法
- Purified
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过滤
- Sterile filtered
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免疫原
- A synthetic peptide corresponding to human RBP2, aa 1416-1434.
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亚型
- IgG2a kappa
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应用备注
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1. Western blotting: ~1 g/mL
2. Immunofluorescence staining
3. Flow Cytometry: 1 g for 10^6 cells -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol
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储存液
- Azide free
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储存条件
- -20 °C
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Genome-wide analysis of the H3K4 histone demethylase RBP2 reveals a transcriptional program controlling differentiation." in: Molecular cell, Vol. 31, Issue 4, pp. 520-30, (2008) (PubMed).
: "RBP2 belongs to a family of demethylases, specific for tri-and dimethylated lysine 4 on histone 3." in: Cell, Vol. 128, Issue 6, pp. 1063-76, (2007) (PubMed).
: "The retinoblastoma binding protein RBP2 is an H3K4 demethylase." in: Cell, Vol. 128, Issue 5, pp. 889-900, (2007) (PubMed).
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Genome-wide analysis of the H3K4 histone demethylase RBP2 reveals a transcriptional program controlling differentiation." in: Molecular cell, Vol. 31, Issue 4, pp. 520-30, (2008) (PubMed).
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- KDM5A (Lysine (K)-Specific Demethylase 5A (KDM5A))
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别名
- KDM5A
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背景
- RBP2 was originally identified as a retinoblastoma binding protein. It is also known as JARID1A (Jumonji, AT rich interactive domain 1A). RBP2 plays both negative and positive roles in RB- mediated transcriptional activation, depending on the kinds of genes and regulates differentiation by its function as an H3K4 histone demethylase.
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UniProt
- P29375
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途径
- Chromatin Binding, Warburg Effect
抗原
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