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KDM5A 抗体 (AA 1416-1434)

This anti-KDM5A antibody is a 小鼠 单克隆 antibody detecting KDM5A in WB, IF 和 FACS. Suitable for 人. This Primary Antibody has been cited in 3+ publications.
产品编号 ABIN3201015
发货至: 中国

Quick Overview for KDM5A 抗体 (AA 1416-1434) (ABIN3201015)

抗原

See all KDM5A 抗体
KDM5A (Lysine (K)-Specific Demethylase 5A (KDM5A))

适用

  • 61
  • 16
  • 4
  • 1
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  • 1

宿主

  • 56
  • 4
小鼠

克隆类型

  • 49
  • 12
单克隆

标记

  • 24
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  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This KDM5A antibody is un-conjugated

应用范围

  • 40
  • 20
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  • 7
  • 5
  • 3
  • 3
  • 2
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  • 1
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Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

克隆位点

18E8
  • 抗原表位

    • 15
    • 8
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 1416-1434

    特异性

    Specific to human and mouse RBP2. Can detect endogenous levels of RBP2.

    纯化方法

    Purified

    过滤

    Sterile filtered

    免疫原

    A synthetic peptide corresponding to human RBP2, aa 1416-1434.

    亚型

    IgG2a kappa
  • 应用备注

    1. Western blotting: ~1 g/mL
    2. Immunofluorescence staining
    3. Flow Cytometry: 1 g for 10^6 cells

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, 50 % glycerol

    储存液

    Azide free

    储存条件

    -20 °C
  • Lopez-Bigas, Kisiel, Dewaal, Holmes, Volkert, Gupta, Love, Murray, Young, Benevolenskaya: "Genome-wide analysis of the H3K4 histone demethylase RBP2 reveals a transcriptional program controlling differentiation." in: Molecular cell, Vol. 31, Issue 4, pp. 520-30, (2008) (PubMed).

    Christensen, Agger, Cloos, Pasini, Rose, Sennels, Rappsilber, Hansen, Salcini, Helin: "RBP2 belongs to a family of demethylases, specific for tri-and dimethylated lysine 4 on histone 3." in: Cell, Vol. 128, Issue 6, pp. 1063-76, (2007) (PubMed).

    Klose, Yan, Tothova, Yamane, Erdjument-Bromage, Tempst, Gilliland, Zhang, Kaelin: "The retinoblastoma binding protein RBP2 is an H3K4 demethylase." in: Cell, Vol. 128, Issue 5, pp. 889-900, (2007) (PubMed).

  • 抗原

    KDM5A (Lysine (K)-Specific Demethylase 5A (KDM5A))

    别名

    KDM5A

    背景

    RBP2 was originally identified as a retinoblastoma binding protein. It is also known as JARID1A (Jumonji, AT rich interactive domain 1A). RBP2 plays both negative and positive roles in RB- mediated transcriptional activation, depending on the kinds of genes and regulates differentiation by its function as an H3K4 histone demethylase.

    UniProt

    P29375

    途径

    Chromatin Binding, Warburg Effect
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