c-MYC 抗体 (pSer62)
(2 references)-
- 抗原 See all c-MYC (MYC) 抗体
- c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))
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抗原表位
- pSer62
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This c-MYC antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF)
- 交叉反应 （详细）
- Expected to react with mouse, rat from the sequence identity.
- 纯化方法
- Purified
- 免疫原
- Synthetic peptide containing pSer62 of cMyc
- 克隆位点
- 33A12E10
- 亚型
- IgG2b kappa
- Top Product
- Discover our top product MYC Primary Antibody
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anti-Myc Proto-Oncogene protein (MYC) (AA 330-439) antibody
MYC 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 1G7 unconjugated
anti-Myc Proto-Oncogene protein (MYC) (Center) antibodyMYC 适用: 人, 小鼠 WB, IF, IP, ICC, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Myc Proto-Oncogene protein (MYC) (AA 31-80) antibodyMYC 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Myc Proto-Oncogene protein (MYC) (pSer62) antibodyMYC 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Myc Proto-Oncogene protein (MYC) (pThr58) antibodyMYC 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Myc Proto-Oncogene protein (MYC) (pSer62) antibodyMYC 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Myc Proto-Oncogene protein (MYC) antibodyKO Validated MYC 适用: 人 WB, IF, ChIP 宿主: 兔 Monoclonal unconjugated
anti-Myc Proto-Oncogene protein (MYC) (AA 101-200) antibodyMYC 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), ICC, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Myc Proto-Oncogene protein (MYC) (N-Term) antibodyMYC 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Myc Proto-Oncogene protein (MYC) antibodyMYC 适用: 人 ELISA 宿主: 小鼠 Monoclonal 7E10 unconjugated
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- 应用备注
- 1. Western blotting: ~1 g/mL
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS, 50 % glycerol
- 储存液
- Azide free
- 储存条件
- -20 °C
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- 抗原
- c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))
- 别名
- C-Myc (MYC 产品)
- 背景
- CMyc is a proto-oncogene, which is overexpressed in a wide range of human cancers. Myc gene encodes a transcription factor that regulates a great number of genes through binding on Enhancer Box sequences (E-boxes) and recruiting histone acetyltransferase. It can also act as a transcriptional repressor. It regulates cell growth, apoptosis, differentiation and stem cell self-renewal. Previous studies on the phosphorylation of c-Myc have suggested functional association between phosphorylation at Thr58/Ser62 by glycogen synthase kinase 3, cyclin dependent kinase, ERK2 and C-Jun N terminal Kinase (JNK), cell proliferation and cell cycle regulation. Phosphorylation at Ser62 is required for Ras-induced stabilization and is prerequisite for phosphorylation at Thr58 for its degradation.
- UniProt
- P01106
- 途径
- p53 Pathway, Cell Division Cycle, Sensory Perception of Sound, Transition Metal Ion Homeostasis, Mitotic G1-G1/S Phases, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Warburg Effect
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