c-MYC 抗体 (pSer62)
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Quick Overview for c-MYC 抗体 (pSer62) (ABIN3201011)
抗原
See all c-MYC (MYC) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- pSer62
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交叉反应 （详细）
- Expected to react with mouse, rat from the sequence identity.
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纯化方法
- Purified
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免疫原
- Synthetic peptide containing pSer62 of cMyc
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亚型
- IgG2b kappa
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anti-Myc Proto-Oncogene protein (MYC) (AA 330-439) antibody
MYC 适用: 人 WB, IF, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1G7 unconjugated
anti-Myc Proto-Oncogene protein (MYC) (Center) antibodyMYC 适用: 人, 小鼠 WB, IF, IP, ICC, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Myc Proto-Oncogene protein (MYC) (AA 31-80) antibodyMYC 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Myc Proto-Oncogene protein (MYC) (pSer62) antibodyMYC 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
anti-Myc Proto-Oncogene protein (MYC) (pThr58) antibodyMYC 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ELISA, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Myc Proto-Oncogene protein (MYC) (pSer62) antibodyMYC 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Myc Proto-Oncogene protein (MYC) (AA 360-440) antibodyMYC 适用: 人, 小鼠, 大鼠 WB, IF, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Myc Proto-Oncogene protein (MYC) (AA 101-200) antibodyMYC 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), ICC, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Myc Proto-Oncogene protein (MYC) (N-Term) antibodyMYC 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
anti-Myc Proto-Oncogene protein (MYC) antibodyMYC 适用: 人 ELISA 宿主: 小鼠 Monoclonal 7E10 unconjugated
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应用备注
- 1. Western blotting: ~1 g/mL
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol
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储存液
- Azide free
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储存条件
- -20 °C
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- c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))
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别名
- C-Myc
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背景
- CMyc is a proto-oncogene, which is overexpressed in a wide range of human cancers. Myc gene encodes a transcription factor that regulates a great number of genes through binding on Enhancer Box sequences (E-boxes) and recruiting histone acetyltransferase. It can also act as a transcriptional repressor. It regulates cell growth, apoptosis, differentiation and stem cell self-renewal. Previous studies on the phosphorylation of c-Myc have suggested functional association between phosphorylation at Thr58/Ser62 by glycogen synthase kinase 3, cyclin dependent kinase, ERK2 and C-Jun N terminal Kinase (JNK), cell proliferation and cell cycle regulation. Phosphorylation at Ser62 is required for Ras-induced stabilization and is prerequisite for phosphorylation at Thr58 for its degradation.
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UniProt
- P01106
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途径
- p53 Pathway, Cell Division Cycle, Sensory Perception of Sound, Transition Metal Ion Homeostasis, Mitotic G1-G1/S Phases, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Warburg Effect
抗原
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