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CD4 抗体

This anti-CD4 antibody is a 大鼠 单克隆 antibody detecting CD4 in FACS 和 IHC (fro). Suitable for 小鼠.
产品编号 ABIN319535
发货至: 中国

Quick Overview for CD4 抗体 (ABIN319535)

抗原

See all CD4 抗体
CD4

适用

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小鼠

宿主

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大鼠

克隆类型

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单克隆

标记

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This CD4 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

克隆位点

YTS191-1
  • 特异性

    This antibody recognises the CD4 cell surface antigen, expressed by a subset of T-lymphocytes. This clone exhibits depleting activity when used in vivo (Antibody SM005LE is recommended for this purpose).

    纯化方法

    Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant

    亚型

    IgG2b
  • 应用备注

    Flow Cytometry: use 10 μL of 1/50-1/100 diluted antibody to label 10^6 cells. Immunohistochemistry on Frozen Sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS, pH 7.4, with 0.09 % sodium azide as preservative

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    CD4

    别名

    CD4

    背景

    CD4 is a single chain transmembraneous glycoprotein (59 kDa) which belongs to the immunoglobulin superfamily. CD4 is present on a subset of T lymphocytes ("helper/inducer" T cells) and is also expressed at a lower level on monocytes, tissue macrophages and granulocytes. The antigen is involved in binding to MHC class II molecules. The intracellular domain of the antigen is associated with p56lck protein tyrosine kinase.Synonyms: T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4

    基因ID

    12504

    NCBI登录号

    NP_038516

    UniProt

    P06332

    途径

    TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events
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