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MAP1LC3A 抗体 (N-Term)

The 兔 多克隆 anti-MAP1LC3A antibody is suitable to detect MAP1LC3A in samples from 人, 小鼠 和 大鼠. It has been validated for WB 和 IF.
产品编号 ABIN319368
发货至: 中国
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Quick Overview for MAP1LC3A 抗体 (N-Term) (ABIN319368)

抗原

See all MAP1LC3A 抗体
MAP1LC3A (Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This MAP1LC3A antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF)
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    N-Term

    序列

    MPSDRPFKQR RSFA

    特异性

    This antibody detects endogenous levels of total LC3A/MAP1LC3A protein.

    交叉反应 (详细)

    Species reactivity (tested):Human, Mouse and Rat

    纯化方法

    Immunoaffinity Chromatography using epitope-specific immunogen

    免疫原

    The antiserum was produced against a synthesized peptide Corresponding to the amino terminal sequence from Human LC3A protein.
  • 应用备注

    Western blot: 1/500approx. 1/1000. Immunofluorescence: 1/100approx. 1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store the antibody (in aliquots) at-20 °C.
  • 抗原

    MAP1LC3A (Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A))

    别名

    LC3

    背景

    Microtubule-associated MAPILC3A constitutes nearly half of the mass of all the microtubule associated proteins that copurify with brain microtubules. MAP1LC3A is one of three human orthologs of the rat Map1LC3, (named MAP1LC3A, MAP1LC3B, and MAP1LC3C). The three isoforms of human MAP1LC3 exhibit distinct expression patterns in different human tissues and also differ in their post-translation modifications. MAP1LC3A and MAP1LC3C are produced by the proteolytic cleavage after the conserved C-terminal Gly residue, MAP1LC3B does not undergo C-terminal cleavage and exists in a single modified form.Synonyms: Autophagy-related protein LC3 A, Autophagy-related ubiquitin-like modifier LC3 A, LC3A, MAP1 light chain 3-like protein 1, MAP1A / 1B light chain 3 A, MAP1A/1B light chain 3 A, MAP1A/MAP1B LC3 A, MAP1LC3A, Microtubule-associated protein 1 light chain 3 alpha, Microtubule-associated proteins 1A/1B light chain 3A

    基因ID

    84557

    NCBI登录号

    NP_115903

    UniProt

    Q9H492

    途径

    Autophagy
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