Glutamate Receptor 1 抗体 (pSer831)
Quick Overview for Glutamate Receptor 1 抗体 (pSer831) (ABIN319113)
抗原
See all Glutamate Receptor 1 (GLUR1) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- pSer831
-
特异性
- This antibody is specific for glutamate receptor subunit 1 (GluR1) when phosphorylated at serine 831.
-
纯化方法
- Affinity chromatography
-
免疫原
- Synthetic phosphopeptide corresponding to amino acid sequence within GluR1 which includes phosphorylated Ser831.
-
亚型
- IgG
-
-
-
-
应用备注
-
Western Blot: 1: 1000, detects a band of approximately 100 kDa in rat brain lysates.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- 10 mM HEPES, pH 7.5 containing 0.09 % Sodium Azide, 0.01 % Bovine Serum Albumin and 50 % Glycerol
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
-
- Glutamate Receptor 1 (GLUR1)
-
别名
- Glutamate Receptor 1 / GLUR1
-
背景
- GluR1, widely expressed throughout the nervous system, is a component of AMPA receptors (alpha-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid receptors), which play a key role at excitatory synapses. Phosphorylation of Ser831 and Ser845 is reported to potentiate GluR1 function, suggesting a possible role in synaptic plasticity, learning and memory.Synonyms: AMPA-selective glutamate receptor 1, AMPA1, GLUH1, GRIA1, GluR-1, GluR-A, GluR-K1, Glutamate receptor ionotropic
-
基因ID
- 2890
-
NCBI登录号
- NP_000818
-
UniProt
- P42261
-
途径
- PI3K-Akt Signaling
抗原
-