CCR8 抗体 (AA 183-201)
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Quick Overview for CCR8 抗体 (AA 183-201) (ABIN319016)
抗原
See all CCR8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 183-201
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特异性
- This antibody recognises the chemokine receptor CCR8, also known as CDw198, which has been identified as a co-receptor for HIV infection. CCR8 is a receptor for the human chemokine 1-309 which is expressed on spleen, thymus and T lymphoblastic cell lines. This antibody detects a band of approximately 50 kDa.
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纯化方法
- Purified
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免疫原
- Peptide corresponding to amino acids 183 to 201 of human CDw198 (CCR8).
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亚型
- IgG
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anti-Chemokine (C-C Motif) Receptor 8 (CCR8) (C-Term) antibody
CCR8 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 8 (CCR8) (Cytoplasmic Domain) antibodyCCR8 适用: 人 ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 8 (CCR8) antibodyCCR8 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 8 (CCR8) antibodyCCR8 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB3350 unconjugated Recombinant Antibody
anti-Chemokine (C-C Motif) Receptor 8 (CCR8) (AA 290-317) antibodyCCR8 适用: 人 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 8 (CCR8) antibodyResearch Grade CCR8 适用: 人 ELISA, FACS 宿主: Humanized Monoclonal 10A11 unconjugated Recombinant Antibody
anti-Chemokine (C-C Motif) Receptor 8 (CCR8) antibodyCCR8 适用: 小鼠 WB, ELISA, IHC (p) 宿主: 山羊 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 8 (CCR8) (Middle Region) antibodyCCR8 适用: 人, Cow WB 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 8 (CCR8) (AA 7-33) antibodyCCR8 适用: 小鼠 WB, ELISA, IHC, IC 宿主: 山羊 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 8 (CCR8) (AA 163-212) antibodyCCR8 适用: 人, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western Blot: 1: 500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Phosphate buffered saline containing 0.02 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- CCR8 (Chemokine (C-C Motif) Receptor 8 (CCR8))
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别名
- CDw198 / CCR8
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背景
- CCR8 is a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation regulated cytokine (TARC) and macrophage inflammatory protein 1 beta (MIP1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. This gene is located at the chemokine receptor gene cluster region. CCR8 expression has been reported in spleen and thymus, natural killer cells, monocytes, and T cells, and at lower levels in peripheral blood leukocytes. CCR8 is also believed to be alternative coreceptor with CD4 for HIV-1 infection.Synonyms: C-C CKR-8, C-C chemokine receptor type 8, CC-CKR-8, CC-chemokine receptor CHEMR1, CCR-8, CKRL1, CMKBR8, CMKBRL2, Chemokine receptor-like 1, GPR-CY6, TER1
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基因ID
- 1237
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NCBI登录号
- NP_005192
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UniProt
- P51685
抗原
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