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RNF34 抗体 (N-Term)

This anti-RNF34 antibody is a 兔 多克隆 antibody detecting RNF34 in WB 和 EIA. Suitable for 人, 小鼠, 大鼠, Cow, 犬 和 灵长类.
产品编号 ABIN318868
发货至: 中国

Quick Overview for RNF34 抗体 (N-Term) (ABIN318868)

抗原

See all RNF34 抗体
RNF34 (Ring Finger Protein 34 (RNF34))

适用

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人, 小鼠, 大鼠, Cow, 犬, 灵长类

宿主

  • 21
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  • 1

克隆类型

  • 24
多克隆

标记

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This RNF34 antibody is un-conjugated

应用范围

  • 22
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Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 9
    • 4
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    AA 1-373, N-Term

    特异性

    This antibody detects Ring Finger homologous to Inhibitor of apoptosis protein (hRFI).

    纯化方法

    Purified

    免疫原

    Recombinant protein corresponding to amino acids 1-373 of human RFI.

    亚型

    IgG
  • 应用备注

    ELISA: 1800 - 1: 4000. Western Blot: 1: 100 - 1: 600, detects a band of approximately 42 kDa.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0mg/mL

    缓冲液

    Phosphate buffered saline pH 7.2 containing 0.01 % Sodium Azide (NaN3)

    储存液

    Sodium azide

    注意事项

    This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    RNF34 (Ring Finger Protein 34 (RNF34))

    别名

    RFI / RNF34

    背景

    RFI is an anti-apoptotic protein which has been shown to be a novel modulator of NF-kB activation, leading to the upregulation of Bcl2 and BclXL. It is also thought to possess E3 ubiquitin protein ligase activity and has been shown to target caspases 8 and 10 for proteasomal degradation. hRFI is expressed ubiquitously, and has been localized to both the nucleus and the cytoplasm. hRFI is also expressed in oesophageal, gastric and colorectal cancers, suggesting a possible association between hRFI and the development of digestive tract cancers.Synonyms: CARP-1, CARP1, Caspases-8 and -10-associated RING finger protein 1, E3 ubiquitin-protein ligase RNF34, FYVE-RING finger protein Momo, Human RING finger homologous to inhibitor of apoptosis protein, RIFF

    基因ID

    80196

    NCBI登录号

    NP_079402

    UniProt

    Q969K3
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