RNF34 抗体 (N-Term)
Our Local Distributor
北京 101111
Quick Overview for RNF34 抗体 (N-Term) (ABIN318868)
抗原
See all RNF34 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 1-373, N-Term
-
特异性
- This antibody detects Ring Finger homologous to Inhibitor of apoptosis protein (hRFI).
-
纯化方法
- Purified
-
免疫原
- Recombinant protein corresponding to amino acids 1-373 of human RFI.
-
亚型
- IgG
-
-
-
-
应用备注
-
ELISA: 1800 - 1: 4000. Western Blot: 1: 100 - 1: 600, detects a band of approximately 42 kDa.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
浓度
- 1.0mg/mL
-
缓冲液
- Phosphate buffered saline pH 7.2 containing 0.01 % Sodium Azide (NaN3)
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
-
- RNF34 (Ring Finger Protein 34 (RNF34))
-
别名
- RFI / RNF34
-
背景
- RFI is an anti-apoptotic protein which has been shown to be a novel modulator of NF-kB activation, leading to the upregulation of Bcl2 and BclXL. It is also thought to possess E3 ubiquitin protein ligase activity and has been shown to target caspases 8 and 10 for proteasomal degradation. hRFI is expressed ubiquitously, and has been localized to both the nucleus and the cytoplasm. hRFI is also expressed in oesophageal, gastric and colorectal cancers, suggesting a possible association between hRFI and the development of digestive tract cancers.Synonyms: CARP-1, CARP1, Caspases-8 and -10-associated RING finger protein 1, E3 ubiquitin-protein ligase RNF34, FYVE-RING finger protein Momo, Human RING finger homologous to inhibitor of apoptosis protein, RIFF
-
基因ID
- 80196
-
NCBI登录号
- NP_079402
-
UniProt
- Q969K3
抗原
-