RAD9A 抗体 (AA 1125-1139)
Our Local Distributor
北京 101111
Quick Overview for RAD9A 抗体 (AA 1125-1139) (ABIN318843)
抗原
See all RAD9A 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 1125-1139
-
纯化方法
- Purified
-
免疫原
- Synthetic peptide corresponding to aa 1125-1139 of yeast Rad9 protein conjugated to Keyhole Limpet Haemocyanin (KLH).
-
亚型
- IgG
-
-
-
-
应用备注
-
ELISA: 1: 2000 - 1: 4000. Western Blot: 1: 50 - 1: 250, detects a band of approximately 60 kDa.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
浓度
- 0.5mg/mL
-
缓冲液
- Phosphate buffered saline pH 7.2 containing 0.09 % Sodium Azide (NaN3)
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
-
- RAD9A (RAD9 Homolog A (S. Pombe) (RAD9A))
-
别名
- RAD9A
-
背景
- In S. cerevisiae this checkpoint is mainly controlled by the PI(3) kinase-like kinase (PIKK) Mec1, which is activated in response to DNA damage. Activated Mec1 hyperphosphorylates Rad9, which in turn triggers the binding of Rad53, the orthologue of mammalian Chk2. Activated Rad53 specifically targets substrates required for cell cycle arrest, gene expression and efficient DNA repair. Mutations affecting Rad9 impair checkpoint induced cell-cycle arrest and increase genomic instability.Synonyms: Cell cycle checkpoint control protein RAD9A, DNA repair exonuclease rad9 homolog A, EC=3.1.11.2, RAD-9A
-
NCBI登录号
- NP_004575
-
UniProt
- Q99638
-
途径
- Positive Regulation of Response to DNA Damage Stimulus
抗原
-