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RAD9A 抗体 (AA 1125-1139)

This anti-RAD9A antibody is a 兔 多克隆 antibody detecting RAD9A in WB 和 EIA. Suitable for Saccharomyces cerevisiae.
产品编号 ABIN318843
发货至: 中国

Quick Overview for RAD9A 抗体 (AA 1125-1139) (ABIN318843)

抗原

See all RAD9A 抗体
RAD9A (RAD9 Homolog A (S. Pombe) (RAD9A))

适用

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Saccharomyces cerevisiae

宿主

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克隆类型

  • 140
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多克隆

标记

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This RAD9A antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

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    AA 1125-1139

    纯化方法

    Purified

    免疫原

    Synthetic peptide corresponding to aa 1125-1139 of yeast Rad9 protein conjugated to Keyhole Limpet Haemocyanin (KLH).

    亚型

    IgG
  • 应用备注

    ELISA: 1: 2000 - 1: 4000. Western Blot: 1: 50 - 1: 250, detects a band of approximately 60 kDa.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0.5mg/mL

    缓冲液

    Phosphate buffered saline pH 7.2 containing 0.09 % Sodium Azide (NaN3)

    储存液

    Sodium azide

    注意事项

    This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    RAD9A (RAD9 Homolog A (S. Pombe) (RAD9A))

    别名

    RAD9A

    背景

    In S. cerevisiae this checkpoint is mainly controlled by the PI(3) kinase-like kinase (PIKK) Mec1, which is activated in response to DNA damage. Activated Mec1 hyperphosphorylates Rad9, which in turn triggers the binding of Rad53, the orthologue of mammalian Chk2. Activated Rad53 specifically targets substrates required for cell cycle arrest, gene expression and efficient DNA repair. Mutations affecting Rad9 impair checkpoint induced cell-cycle arrest and increase genomic instability.Synonyms: Cell cycle checkpoint control protein RAD9A, DNA repair exonuclease rad9 homolog A, EC=3.1.11.2, RAD-9A

    NCBI登录号

    NP_004575

    UniProt

    Q99638

    途径

    Positive Regulation of Response to DNA Damage Stimulus
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