PPARD 抗体 (N-Term)
Our Local Distributor
北京 101111
Quick Overview for PPARD 抗体 (N-Term) (ABIN318837)
抗原
See all PPARD 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 1-14, N-Term
-
特异性
- This antibody detects peroxisome proliferator-activated receptor, delta (PPARD).
-
纯化方法
- Purified
-
免疫原
- Syntetic peptide corresponding to amino acids 1-14 of mouse PPAR delta.
-
亚型
- IgG
-
-
-
-
应用备注
-
ELISA: 1: 2000 - 1: 8000. Western Blot: 1: 500 - 1: 2000, detects a band of approximately 55 kDa in heart whole celllysates.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
浓度
- 1.0mg/mL
-
缓冲液
- Phosphate buffered saline pH 7.2 containing 0.01 % Sodium Azide (NaN3)
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
-
- PPARD (Peroxisome Proliferator-Activated Receptor delta (PPARD))
-
别名
- PPAR-delta
-
背景
- PPARD is a member of the nuclear hormone receptor subfamily. Upon activation, PPARD forms heterodimers with retinoid X receptors (RXRs), and functions to regulate transcription of specific gene sequences. PPARD controls genes involved in lipid metabolism, and enhances fatty acid catabolism and energy uncoupling in adipose tissue and skeletal muscle. PPARD has also been implicated in the proliferation and differentiation of preadipocytes, enterocytes, keratinocytes and the placenta. PPARD agonists could be used therapeutically to target multiple components of the metabolic syndrome, including insulin resistance, hyperglycemia, dyslipidemia, and atherosclerosis.Synonyms: NR1C2, NUCI, Nuclear hormone receptor 1, Nuclear receptor subfamily 1 group C member 2, PPAR-beta, PPARB, PPARD, Peroxisome proliferator-activated receptor delta
-
基因ID
- 19015
-
NCBI登录号
- NP_035275
-
UniProt
- P35396
-
途径
- Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Monocarboxylic Acid Catabolic Process, Smooth Muscle Cell Migration, Positive Regulation of fat Cell Differentiation
抗原
-