PPARA 抗体 (N-Term)
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Quick Overview for PPARA 抗体 (N-Term) (ABIN318836)
抗原
See all PPARA 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-18, N-Term
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特异性
- This antibody detects an epitope within the N-terminal region of human peroxisome proliferator-activated receptor, alpha (PPARA).
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纯化方法
- Purified
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免疫原
- Synthetic peptide corresponding to amino acids 1-18 of human PPAR alpha.
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亚型
- IgG
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anti-Peroxisome Proliferator-Activated Receptor alpha (PPARA) (AA 301-400) antibody
PPARA 适用: 人, 小鼠, 大鼠, 小鸡 WB, ELISA, FACS, IF (p), IF (cc), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Peroxisome Proliferator-Activated Receptor alpha (PPARA) (AA 61-170) antibodyPPARA 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Peroxisome Proliferator-Activated Receptor alpha (PPARA) (AA 1-120) antibodyPPARA 适用: 人, 猴 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 5D10C3 unconjugated
anti-Peroxisome Proliferator-Activated Receptor alpha (PPARA) (AA 1-468) antibodyPPARA 适用: 人, 小鼠 WB, FACS, IF, IHC (p) 宿主: 小鼠 Monoclonal 1331CT894-186-143 unconjugated
anti-Peroxisome Proliferator-Activated Receptor alpha (PPARA) (N-Term) antibodyKO Validated PPARA 适用: 人 WB, IP, IHC (p), ChIP 宿主: 兔 Polyclonal unconjugated
anti-Peroxisome Proliferator-Activated Receptor alpha (PPARA) (AA 1-120) antibodyPPARA 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 5D10E10 unconjugated
anti-Peroxisome Proliferator-Activated Receptor alpha (PPARA) (C-Term) antibodyPPARA 适用: 人, 小鼠, 大鼠, 犬, 马, Cow, Pig, 山羊, 豚鼠, 兔, 绵羊, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Peroxisome Proliferator-Activated Receptor alpha (PPARA) (N-Term) antibodyPPARA 适用: 人, 小鼠 WB, ELISA, IHC, FACS, IF, FM 宿主: 兔 Polyclonal unconjugated
anti-Peroxisome Proliferator-Activated Receptor alpha (PPARA) (pSer12) antibodyPPARA 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IF (p), IF (cc), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Peroxisome Proliferator-Activated Receptor alpha (PPARA) (N-Term) antibodyPPARA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1: 8000 - 1: 32000. Western Blot: 1: 500 - 1: 1000, detects a band of approximately 52 kDa in 3T3 whole celllysate.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0mg/mL
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缓冲液
- Phosphate buffered saline pH 7.2 containing 0.09 % Sodium Azide (NaN3)
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储存液
- Sodium azide
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注意事项
- This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- PPARA (Peroxisome Proliferator-Activated Receptor alpha (PPARA))
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别名
- PPAR-alpha
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背景
- PPARA is a member of the nuclear hormone receptor subfamily. Upon activation, PPARA forms heterodimers with retinoid X receptors (RXRs), and functions to regulate transcription of specific gene sequences. In particular, PPARA controls genes involved in the peroxisomal and mitochondrial beta oxidation pathways, fatty acid uptake, and triglyceride catabolism in the liver and skeletal muscle. PPARA also has anti-inflammatory and anti-proliferative effects and prevents the proatherogenic effects of cholesterol accumulation in macrophages by stimulating cholesterol efflux. PPARA is the main target of fibrate drugs, hypolipidemic agents used in the treatment of dyslipidemia and the prevention of cardiovascular disease. They could also be used for the treatment of type II diabetes.Synonyms: NR1C1, Nuclear receptor subfamily 1 group C member 1, PPAR, PPARA, Peroxisome proliferator-activated receptor alpha
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基因ID
- 5465
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NCBI登录号
- NP_001001928
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UniProt
- Q07869
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途径
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process, Hepatitis C
抗原
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