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UNG 抗体 (N-Term)

UNG 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN318787
发货至: 中国
  • 抗原 See all UNG 抗体
    UNG (Uracil-DNA Glycosylase (UNG))
    抗原表位
    • 7
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 49
    • 28
    • 24
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 42
    • 7
    克隆类型
    • 44
    • 5
    多克隆
    标记
    • 38
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This UNG antibody is un-conjugated
    应用范围
    • 35
    • 16
    • 13
    • 13
    • 11
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    特异性
    This antibody recognises uracil-DNA glycosylase 1 (UNG1), a member of the uracil-DNA glycosylase and cyclin family.
    纯化方法
    Purified
    免疫原
    14 amino acid peptide sequence near the amino terminus of human UNG1.
    亚型
    IgG
    Top Product
    Discover our top product UNG Primary Antibody
  • 应用备注
    Western Blot: 0.5 - 1.0g/mL, detects a band of approximately 34.6 kDa in C2C/2 celllysates.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate buffered saline containing 0.02 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原
    UNG (Uracil-DNA Glycosylase (UNG))
    Abstract
    UNG 产品
    别名
    DGU antibody, HIGM4 antibody, HIGM5 antibody, UDG antibody, UNG1 antibody, UNG15 antibody, UNG2 antibody, ung antibody, zgc:56102 antibody, PSPTO4236 antibody, BA5648 antibody, ECK2578 antibody, JW2564 antibody, An02g14790 antibody, AO090001000732 antibody, DDBDRAFT_0204444 antibody, DDBDRAFT_0214910 antibody, DDB_0204444 antibody, DDB_0214910 antibody, uracil-DNA glycosylase antibody, uracil DNA glycosylase antibody, uracil DNA glycosylase a antibody, uracil-DNA glycosylase Ung antibody, uracil-DNA-glycosylase antibody, uracil DNA glycosylase L homeolog antibody, uracil glycosylase antibody, temporal expression: early antibody, ung antibody, ung2 antibody, Ung antibody, UNG antibody, unga antibody, STY2840 antibody, ung.L antibody, ANI_1_3358024 antibody, AOR_1_1318164 antibody, uglA antibody, Arnit_2731 antibody, D4R antibody
    物质类
    Viral Protein
    背景
    Two isoforms of UNG exist, isoform 1 is expressed in the mitochondria of in skeletal muscle, heart and testicles while isoform 2 (UNG2) is more abundant in proliferating tissues and expressed in the nucleus. Uracil residues can be misincorporated into DNA by DNA polymerase or by deamination of cytosine. UNG1 is a major enzyme in base excision repair, excising the misincorporated uracil residues in a process crucial to increasing immunoglobulin diversity. In association with activation-induced cytosine deaminase, UNG is also essential to the generation of strand breaks that initiate class switch recombination. UNG is also involved in the innate immune response against retroviral infections, HIV-1 accessory protein Vpr induces the rapid degradation of UNG2.Synonyms: DGU, UDG, UNG1, UNG15
    基因ID
    7374
    NCBI登录号
    NP_003353
    UniProt
    P13051
    途径
    DNA Damage Repair, Production of Molecular Mediator of Immune Response
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