UNG 抗体 (N-Term)
Quick Overview for UNG 抗体 (N-Term) (ABIN318787)
抗原
See all UNG 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- This antibody recognises uracil-DNA glycosylase 1 (UNG1), a member of the uracil-DNA glycosylase and cyclin family.
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纯化方法
- Purified
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免疫原
- 14 amino acid peptide sequence near the amino terminus of human UNG1.
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亚型
- IgG
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anti-Uracil-DNA Glycosylase (UNG) (AA 1-313) antibody
UNG 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Uracil-DNA Glycosylase (UNG) antibodyUNG 适用: 人, 猴 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 1G2 unconjugated
anti-Uracil-DNA Glycosylase (UNG) (AA 1-304) antibodyUNG 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Uracil-DNA Glycosylase (UNG) (AA 114-224) antibodyUNG 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Uracil-DNA Glycosylase (UNG) (Internal Region) antibodyUNG 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Uracil-DNA Glycosylase (UNG) (AA 281-298) antibodyUNG 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Uracil-DNA Glycosylase (UNG) (AA 1-304) antibodyUNG 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Uracil-DNA Glycosylase (UNG) (AA 1-100) antibodyUNG 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Uracil-DNA Glycosylase (UNG) (AA 1-313) antibodyUNG 适用: 人 WB, ELISA, IF, ICC 宿主: 小鼠 Monoclonal k1C12 unconjugated
anti-Uracil-DNA Glycosylase (UNG) (N-Term) antibodyUNG 适用: 人, 小鼠 WB, ELISA, IHC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western Blot: 0.5 - 1.0g/mL, detects a band of approximately 34.6 kDa in C2C/2 celllysates.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline containing 0.02 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- UNG (Uracil-DNA Glycosylase (UNG))
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背景
- Two isoforms of UNG exist, isoform 1 is expressed in the mitochondria of in skeletal muscle, heart and testicles while isoform 2 (UNG2) is more abundant in proliferating tissues and expressed in the nucleus. Uracil residues can be misincorporated into DNA by DNA polymerase or by deamination of cytosine. UNG1 is a major enzyme in base excision repair, excising the misincorporated uracil residues in a process crucial to increasing immunoglobulin diversity. In association with activation-induced cytosine deaminase, UNG is also essential to the generation of strand breaks that initiate class switch recombination. UNG is also involved in the innate immune response against retroviral infections, HIV-1 accessory protein Vpr induces the rapid degradation of UNG2.Synonyms: DGU, UDG, UNG1, UNG15
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基因ID
- 7374
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NCBI登录号
- NP_003353
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UniProt
- P13051
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途径
- DNA Damage Repair, Production of Molecular Mediator of Immune Response
抗原
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