IL23A 抗体 (C-Term)
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Quick Overview for IL23A 抗体 (C-Term) (ABIN318744)
抗原
See all IL23A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody detects an epitope within the C-terminal (CT) domain of Human Interleukin-23 (IL-23).
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交叉反应 （详细）
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Species reactivity (expected):Mouse.
Species reactivity (tested):Human. -
纯化方法
- Purified
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免疫原
- A 14 amino acid peptide from near the carboxy-terminus of human IL-23
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亚型
- IgG
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anti-Interleukin 23, alpha subunit p19 (IL23A) (C-Term) antibody
IL23A 适用: 人 WB, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 23, alpha subunit p19 (IL23A) (AA 1-189) antibodyIL23A 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4C8 unconjugated
anti-Interleukin 23, alpha subunit p19 (IL23A) (AA 20-189) antibodyIL23A 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 23, alpha subunit p19 (IL23A) (N-Term) antibodyIL23A 适用: 人, 小鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 23, alpha subunit p19 (IL23A) (AA 20-155) antibodyIL23A 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 23, alpha subunit p19 (IL23A) (AA 33-67) antibodyIL23A 适用: 人, 小鼠 WB, FACS 宿主: 兔 Polyclonal RB56752 unconjugated
anti-Interleukin 23, alpha subunit p19 (IL23A) (AA 1-189) antibodyIL23A 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 23, alpha subunit p19 (IL23A) antibodyIL23A 适用: 人 WB, ELISA 宿主: 兔 Monoclonal 1F6 unconjugated Recombinant Antibody
anti-Interleukin 23, alpha subunit p19 (IL23A) (AA 1-189) antibodyIL23A 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Interleukin 23, alpha subunit p19 (IL23A) antibodyIL23A 适用: 人 WB, ELISA 宿主: 大鼠 Monoclonal I 178G unconjugated
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应用备注
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Immunohistochemistry on frozen sections: 10g/mL. Western Blot: 1 - 2g/mL, detects a band of approximately 24 kDa in Raji cell lysates
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), 0.02 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- IL23A (Interleukin 23, alpha subunit p19 (IL23A))
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别名
- Interleukin-23 alpha / IL23A
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背景
- IL23 is a 21kD heterodimeric cytokine structurally related to IL-12. IL-23 is composed of a p19 subunit encoded by the IL23A gene, and a p40 subunit of interleukin-12 (IL12B). IL-23 is expressed mainly by activated macrophages and dendritic cells, and plays an important role in bridging innate and adaptive responses. IL-23 activates a subset of T cells called Th17 cells, which are characterised by the production of interleukin-17. The IL-23/IL-17 pathway is essential for the induction and maintenance of brain and joint inflammatory autoimmune diseases, including Guillain Barre Syndrome, Multiple sclerosis and rheumatoid arthritis.Synonyms: IL-23 subunit alpha, IL-23p19, Interleukin-23 subunit p19, SGRF
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基因ID
- 51561
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NCBI登录号
- NP_057668
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UniProt
- Q9NPF7
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
抗原
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