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NOXA 抗体 (N-Term)

PMAIP1 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN318707
发货至: 中国
  • 抗原 See all NOXA (PMAIP1) 抗体
    NOXA (PMAIP1) (Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1))
    抗原表位
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    人, 小鼠, 大鼠
    宿主
    • 29
    • 6
    • 1
    • 1
    克隆类型
    • 22
    • 15
    多克隆
    标记
    • 19
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This NOXA antibody is un-conjugated
    应用范围
    • 17
    • 9
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody recognises murine Noxa.
    纯化方法
    Purified
    免疫原
    Synthetic peptide corresponding to N-terminus of mouse NOXA.
    亚型
    IgG
    Top Product
    Discover our top product PMAIP1 Primary Antibody
  • 应用备注
    Western Blot: 0.5 - 1.0g/mL, detects a band of approximately 11 kDa in human stomach celllysates.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5mg/mL
    缓冲液
    Phosphate buffered saline containing 0.02 % Sodium Azide (NaN3)
    储存液
    Sodium azide
    注意事项
    This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    NOXA (PMAIP1) (Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1))
    别名
    NOXA (PMAIP1 产品)
    别名
    TN3 antibody, PMAIP1 antibody, zgc:162379 antibody, APR antibody, NOXA antibody, Noxa antibody, phorbol-12-myristate-13-acetate-induced protein 1 antibody, PMAIP1 antibody, pmaip1 antibody, Pmaip1 antibody
    背景
    Noxa is an 11 kDa member of the BH3-only proapoptotic protein family. Noxa is localised to the mitochondria and is a transcriptional target of p73, p53 and BH3-only proteins. It is thought to induce apoptosis when activated, lowering the activity of anti-apoptotic Bcl-2-like proteins. It can be upregulated by mitogenic activation, independently of p53. In humans, along with Mcl-1 it is thought to form a selective pathway that restrains lymphocyte proliferation.Synonyms: PMA-induced protein 1, PMAIP1, Phorbol-12-myristate-13-acetate-induced protein 1
    基因ID
    5366
    NCBI登录号
    NP_066950
    UniProt
    Q13794
    途径
    p53 Pathway, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus
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