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NGFR 抗体

This anti-NGFR antibody is a 兔 多克隆 antibody detecting NGFR in WB 和 IF. Suitable for 人 和 小鼠.
产品编号 ABIN318704
发货至: 中国

Quick Overview for NGFR 抗体 (ABIN318704)

抗原

See all NGFR 抗体
NGFR (Nerve Growth Factor Receptor (NGFR))

适用

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人, 小鼠

宿主

  • 110
  • 99
  • 4
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克隆类型

  • 138
  • 76
多克隆

标记

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This NGFR antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF)
  • 特异性

    This antibody recognises CD271, a transmembrane protein of 70-75 kDa, otherwise known as Nerve Growth Factor Receptor (NGFR).

    纯化方法

    Purified

    免疫原

    Recombinant human CD271

    亚型

    IgG
  • 应用备注

    Western Blot: 1g/mL, detects a band of approximately 75-80 kDa in A-20 cell lysate.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0mg/mL

    缓冲液

    Phosphate buffered saline containing 0.02 % Sodium Azide (NaN3)

    储存液

    Sodium azide

    注意事项

    This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    NGFR (Nerve Growth Factor Receptor (NGFR))

    别名

    CD271 / NGFR

    背景

    CD 271 is a pro-apoptotic member of the tumour necrosis factor receptor (TNFR) family and its ligands include NGF, brain derived growth neurotrophic factor (BDNF), NT3 and NT4. CD271 has been shown to interact with tropomyosin-receptor-kinase A (TrkA) forming the high-affinity NGF receptor, while CD271 can signal alone, constituting the low-affinity NGF receptor. When signalling alone, CD271 is involved in apoptosis, neurite outgrowth during development and myelination. Mutations and changes in CD271 expression have been implicated in various pathological diseases including AlzheimerSynonyms: TNFRSF16, Tumor necrosis factor receptor superfamily member 16

    基因ID

    4804

    NCBI登录号

    NP_002498

    UniProt

    P08138

    途径

    NF-kappaB Signaling, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Growth Factor Binding
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