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Nerve Growth Factor 抗体

This anti-Nerve Growth Factor antibody is a 兔 多克隆 antibody detecting Nerve Growth Factor in WB, Func 和 EIA. Suitable for 人 和 小鼠.
产品编号 ABIN318395
发货至: 中国

Quick Overview for Nerve Growth Factor 抗体 (ABIN318395)

抗原

See all Nerve Growth Factor (NGF) 抗体
Nerve Growth Factor (NGF)

适用

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人, 小鼠

宿主

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  • 1
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克隆类型

  • 73
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  • 1
多克隆

标记

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This Nerve Growth Factor antibody is un-conjugated

应用范围

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Western Blotting (WB), Functional Studies (Func), Enzyme Immunoassay (EIA)
  • 特异性

    This antibody recognizes both the 2.5S and 7S forms of Mouse NGF beta, a secreted peptide involved in the development and maintenance of the sympathetic and sensory nervous systems. In a standard bioassay, this antibody neutralises the activity of 3.0 ng/mL NGF 2.5S when used at a concentration of around 0.5 μg/mL.

    纯化方法

    Affinitv Chromatography

    免疫原

    Affinity purified Mouse 2.5S NGF

    亚型

    IgG
  • 应用备注

    ELISA.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 溶解方式

    Restore with 1.0 mL distilled water. Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. We recommend that the vial is gently mixed after reconstitution. For long term storage the addition of 0.09 % Sodium Azide is recommended. For Functional Studies do not Add Sodium Azide.

    浓度

    1.0 mg/mL

    缓冲液

    PBS, None, None

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store undiluted at -20 °C.
  • 抗原

    Nerve Growth Factor (NGF)

    别名

    NGF

    背景

    Nerve growth factor (NGF) is one of a family of neurotrophins that induce the survival and proliferation of neurons. In cell culture, NGF induces the formation of neurite projections and, in vivo, may stimulate the innervation of tissues. NGF plays a role in the repair, regeneration, and protection of neurons, and as such could serve as a therapeutic agent in neurodegenerative conditions such as Alzheimer's disease. NGF enhances survival, growth, neurotransmitter biosynthesis of sympathetic and sensory neurons, neurotrophic factor, cutaneous innervation, growth, differentiation and survival of B lymphocytes. It also has a possible role in allergy and tissue repair. NGF is found in the hypothalamus, pituitary, thyroid gland, testes, epididymis, vascular smooth muscle cells, fibroblasts, mast cells and eosinophils. NGF is upregulated by glutamate, vitamin D3, IL6, FGF basic, astrocyte specific IL1, TNF alpha, PDGF and TGF beta. It is downregulated by GABAergic neuronal activity, glucocorticoids and Schwann cell-specific TGF beta.Synonyms: Beta-NGF, Beta-nerve growth factor, NGFB

    基因ID

    4803

    NCBI登录号

    NP_002497

    UniProt

    P01138

    途径

    Regulation of Cell Size
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