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Paxillin 抗体 (pTyr118)

This 兔 多克隆 antibody specifically detects Paxillin in WB. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN318100
发货至: 中国
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Quick Overview for Paxillin 抗体 (pTyr118) (ABIN318100)

抗原

See all Paxillin (PXN) 抗体
Paxillin (PXN)

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This Paxillin antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    pTyr118

    特异性

    Paxillin antibody detects endogenous levels of Paxillin pTyr118 protein.

    纯化方法

    Affinity Chromatography using epitope-specific immunogen.
  • 应用备注

    ELISA: 1/10000-1/20000. Western Blot: 1/500-1/1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH ~7.2 containing 15 mM Sodium Azide as preservative.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    Paxillin (PXN)

    别名

    Paxillin / PXN

    背景

    Paxillin is a 64 kDa cytoskeletal adapter protein involved in organisation and function of focal adhesions, which are critical to cell adhesion and migration. This in turn plays a role in a wide variety of processes including embryogenesis, organogenesis, wound repair, inflammation and cancer. Paxillin contains LD motifs, LIM domains, SH3 and SH2 binding domains that serve as docking sites for cytoskeletal proteins, tyrosine kinases (e.g., FAK, Pyk 2, Src), serine/threonine kinases, GTPase activating proteins and other adaptor proteins (e.g., Actin, Vinculin, Crk).Synonyms: FLJ16691

    分子量

    approx. 70 kDa

    基因ID

    5829

    NCBI登录号

    NP_001074324

    UniProt

    P49023

    途径

    MAPK Pathway, EGFR Signaling Pathway, Response to Growth Hormone Stimulus, Cell-Cell Junction Organization, Maintenance of Protein Location, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling
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