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ErbB2/Her2 抗体 (pTyr1221, pTyr1222)

This anti-ErbB2/Her2 antibody is a 兔 多克隆 antibody detecting ErbB2/Her2 in WB, IP 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN318035
发货至: 中国

Quick Overview for ErbB2/Her2 抗体 (pTyr1221, pTyr1222) (ABIN318035)

抗原

See all ErbB2/Her2 抗体
ErbB2/Her2 (Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This ErbB2/Her2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    pTyr1221, pTyr1222

    特异性

    This antibody detects endogenous levels of HER2 pTyr1221/1222 protein.

    纯化方法

    Affinity Chromatography using epitope-specific immunogen.
  • 应用备注

    ELISA: 1/20000-1/40000. Western Blot: 1/500-1/1000. Immunohistochemistry: 1/50-1/200. Immunoprecipitation: 1/50-1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH ~7.2 containing 0.05 % Sodium Azide as preservative.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    ErbB2/Her2 (Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2))

    别名

    CD340 / ERBB2 / HER2

    背景

    ErbB 2 is a receptor tyrosine kinase of the ErbB 2 family. It is closely related instructure to the epidermal growth factor receptor. ErbB 2 oncoprotein is detectable in a proportion of breast and other adenocarconomas, as well as transitional cell carcinomas. In the case of breast cancer, expression determined by immunohistochemistry has been shown to be associated with poor prognosis.Synonyms: HER-2, MNL19, NEU, NEU proto-oncogene, NGL, Receptor tyrosine-protein kinase erbB-2, Tyrosine kinase-type cell surface receptor HER2, c-erbB-2, p185erbB2

    分子量

    approx. 150-170 kDa

    基因ID

    2064

    NCBI登录号

    NP_001005862

    UniProt

    P04626

    途径

    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Skeletal Muscle Fiber Development
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