NHE7 抗体
Quick Overview for NHE7 抗体 (ABIN317937)
抗原
See all NHE7 (SLC9A7) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- NHE-7 antibody detects endogenous levels of NHE-7 protein.(region surrounding Asp566)
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纯化方法
- Affinity chromatography
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anti-Sodium Hydrogen Exchanger 7 (SLC9A7) (Internal Region) antibody
SLC9A7 适用: 人, 小鼠, 大鼠 ELISA, WB, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Sodium Hydrogen Exchanger 7 (SLC9A7) antibodySLC9A7 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sodium Hydrogen Exchanger 7 (SLC9A7) (C-Term) antibodySLC9A7 适用: 人, 小鼠, 大鼠, 兔, Cow, 马, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Sodium Hydrogen Exchanger 7 (SLC9A7) (AA 29-78) antibodySLC9A7 适用: 人, 小鼠, 大鼠, 豚鼠, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Sodium Hydrogen Exchanger 7 (SLC9A7) (N-Term) antibodySLC9A7 适用: 人, 小鼠, 兔, 豚鼠, 犬, 斑马鱼, 山羊 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- NHE7 (SLC9A7) (Sodium Hydrogen Exchanger 7 (SLC9A7))
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别名
- SLC9A7 / NHE7
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背景
- Na+/H+ exchangers (NHE) of mammalian cells are plasma membrane intrinsic proteins mediating exchange of N+ and H+ ions in various tissues. The NHE catalyzes the electroneural transport of extracellular Na+ for intracellular H+. They play a major role in regulation of intracellular pH ( pH i) in addition to trans-cellular absorption of Na+, cell volume regulation and possibly in cell proliferation. These primary functions of the Na+/H+ exchanger have been related to many pathophysiological states, include hypertension, organ growth and hypertrophy, regression of cancer and renal intestinal disorders. At least 7 NHE isoforms (NHE1-7) have been cloned so far. They are all similar in their primary structure and predicted to have 10-12 transmembrane domains. The C-terminal domain of NHEs are predicted to be intracellular. NHE7 (human 725 aa, chromosome Xp11.4) is ubiquitously expressed, and predominantly localizes to the trans-golgi network. NHE7 mediates the influx of Na+ or K+ in exchange for H+. It is ~70 % related to NHE6 but relatively less (~25 %) homologous with other NHEs.Synonyms: NHE-7, Na(+)/H(+) exchanger 7, Sodium/hydrogen exchanger 7, Solute carrier family 9 member 7
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分子量
- approx. 80 kDa
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基因ID
- 84679
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NCBI登录号
- NP_115980
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UniProt
- Q96T83
抗原
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