NHE7 抗体 (Extracellular, Loop 2)
Our Local Distributor
北京 101111
Quick Overview for NHE7 抗体 (Extracellular, Loop 2) (ABIN7237818)
抗原
See all NHE7 (SLC9A7) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 158-171, Extracellular, Loop 2
-
原理
- A Rabbit Polyclonal antibody to Na+/H+ Exchanger 7 (NHE7) (extracellular)
-
交叉反应
- 人, 小鼠, 大鼠
-
预测反应
- Rat - identical, Human - 13 out of 14 amino acid residues identical
-
产品特性
- Extracellular, 2nd loop
-
纯化方法
- Affinity purified on immobilized antigen.
-
免疫原
- (C)EISPGKINNVEQND, corresponding to amino acid residues 158 - 171 of mouse SLC9A7
-
亚型
- IgG
-
-
anti-Sodium Hydrogen Exchanger 7 (SLC9A7) (Internal Region) antibody
SLC9A7 适用: 人, 小鼠, 大鼠 ELISA, WB, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Sodium Hydrogen Exchanger 7 (SLC9A7) antibodySLC9A7 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sodium Hydrogen Exchanger 7 (SLC9A7) (C-Term) antibodySLC9A7 适用: 人, 小鼠, 大鼠, 兔, Cow, 马, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Sodium Hydrogen Exchanger 7 (SLC9A7) (AA 29-78) antibodySLC9A7 适用: 人, 小鼠, 大鼠, 豚鼠, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Sodium Hydrogen Exchanger 7 (SLC9A7) (N-Term) antibodySLC9A7 适用: 人, 小鼠, 兔, 豚鼠, 犬, 斑马鱼, 山羊 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
WB: 1:200
FC: 5 μg per reaction
ICC: The optimal concentration should be determined by the user
IHC: 1:200
IP: The optimal concentration should be determined by the user
-
说明
-
Negative Control: (ABIN7236882)
Blocking Peptide: (ABIN7236882)
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- 25 μL, 50 μL or 0.2 mL double distilled water (DDW), depending on the sample size.
-
浓度
- 0.8 mg/mL
-
缓冲液
- PBS pH 7.4, 1 % BSA with 0.05 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C
-
-
- NHE7 (SLC9A7) (Sodium Hydrogen Exchanger 7 (SLC9A7))
-
别名
- SLC9A7
-
背景
-
Synonyms: Sodium/hydrogen exchanger 7, Solute Carrier Family 9 Member A7, SLC9A7, NHE-7
Description: Na+/H+ exchangers (NHEs) also termed solute carrier family 9 (SLC9), are proteins that function as ion transporters. NHEs are present across all kingdoms of life from prokaryotes to eukaryotes and are found to be crucial in preventing intracellular acidification. NHEs are divided into 3 groups SLC9A (NHE1-9), SLC9B (NHA1 and NHA2) and SLC9C according to their cellular location and their function. NHEs regulates cell volume and pH of the cytosol and organelles1.NHE7 is an NHE that is localized predominantly to the trans-Golgi network (TGN) and post-Golgi vesicles. NHE7 differ from other NHEs by its ability to transport both Na+ and K+ via a H+ gradient-dependent manner2. NHE7 mRNA is expressed in wide range of cells but is especially abundant in the brain, skeletal muscle and various secretory tissues3. The predicted membrane topology of NHE7 consist of 12 transmembrane domains (TMDs) and a single N-glycosylation site at position 145. Similarly to the other SLC9A isoforms NHE7 can be assembled as a homodimer. It was recently found that a missense variant in NHE7 associates with multigenerational nonsyndromic intellectual disability (ID)3.
-
基因ID
- 84679
-
NCBI登录号
- NM_032591
-
UniProt
- Q96T83
抗原
-
